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Brief Title: Study to Assess the Safety and Tolerability of a PARP Inhibitor in Combination With Topotecan
Official Title: A Phase I, Open-Label, Study of the Safety and Tolerability of KU-0059436 and Topotecan in the Treatment of Patients With Advanced Solid Tumours
Study ID: NCT00516438
Brief Summary: The purpose of this study is to identify a safe and tolerable dose of the drug KU-0059436 that can be given in combination with topotecan chemotherapy in patients with advanced solid tumours
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Research Site, Glasgow, , United Kingdom
Research Site, Leicester, , United Kingdom
Research Site, Manchester, , United Kingdom
Name: James Cassidy
Affiliation: Beaston Oncology Centre, Glasgow, UK
Role: PRINCIPAL_INVESTIGATOR
Name: James Carmichael, BSc MBChB MD FRCP
Affiliation: KuDOS Pharmaceutical Ltd
Role: STUDY_DIRECTOR