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Spots Global Cancer Trial Database for Study of Zanubrutinib (BGB-3111) in Participants With Marginal Zone Lymphoma

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Trial Identification

Brief Title: Study of Zanubrutinib (BGB-3111) in Participants With Marginal Zone Lymphoma

Official Title: A Phase 2, Open-label Study of Zanubrutinib (BGB-3111) in Patients With Relapsed or Refractory Marginal Zone Lymphoma

Study ID: NCT03846427

Interventions

Zanubrutinib

Study Description

Brief Summary: This is a single arm study to evaluate the efficacy, safety and tolerability of zanubrutinib (BGB-3111) in participants with relapsed/refractory marginal zone lymphoma (R/R MZL).

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Clinical Research Alliance, Inc., Westbury, New York, United States

The Charlotte-Mecklenburg Hospital Authority, Charlotte, North Carolina, United States

Canberra Hospital, Garran, Australian Capital Territory, Australia

Concord Repatriation General Hospital, Concord, New South Wales, Australia

St George Hospital, Kogarah, New South Wales, Australia

Princess Alexandra Hospital (AUS), Woolloongabba, Queensland, Australia

Flinders Medical Centre, Bedford Park, South Australia, Australia

Box Hill Hospital (AUS), Box Hill, Victoria, Australia

Monash Medical Centre, Clayton, Victoria, Australia

Peninsula Private Hospital, Frankston, Victoria, Australia

Henan Cancer Hospital, Zhengzhou, Henan, China

Institute of Hematology and Hospital of Blood Disease, Tianjin, Tianjin, China

The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China

Peking University Third Hospital, Beijing, , China

Fakultni nemocnice Kralovske Vinohrady, Praha 10, , Czechia

Hopital de la Conception - APHM, Marseille Cedex 05, Bouches-du-Rhône, France

Centre de Lutte Contre Le Cancer - Institut Bergonie, Bordeaux, , France

Hôpital Saint-Louis, Paris, , France

Centre Hospitalier Lyon Sud, Pierre-Bénite, , France

Azienda Ospedaliera Universitaria Policlinico Sant'Orsola Malpighi, Bologna, , Italy

Azienda Socio Sanitaria Territoriale Niguarda (Grande Ospedale Metropolitano Niguarda), Milano, , Italy

A.O.U. Policlinico di Modena, Modena, , Italy

Azienda Ospedaliero - Universitaria Maggiore delle Carità, Novara, , Italy

Azienda Ospedaliera S. Maria Di Terni, Terni, , Italy

Severence Hospital, Seoul, , Korea, Republic of

North Shore Hospital (NZ), Auckland, , New Zealand

Auckland City Hospital, Auckland, , New Zealand

University College London Hospitals, London, Greater London, United Kingdom

Royal Marsden Hospital- London, London, Greater Longon, United Kingdom

The Christie, Manchester, Greater Manchester, United Kingdom

Beatson West of Scotland Cancer Centre, Glasgow, Strathclyde, United Kingdom

Contact Details

Name: Study Director

Affiliation: BeiGene

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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