Spots Global Cancer Trial Database for Predictive Factors for Medullary Thyroid Cancer Aggressiveness
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Trial Identification
Brief Title: Predictive Factors for Medullary Thyroid Cancer Aggressiveness
Official Title: Predective Factors for Tumor Aggressiveness in Medullary Thyroid Cancer
Study ID: NCT06292988
Conditions
Interventions
Study Description
Brief Summary: This study is a retrospective study trying to find the predictive factors for medullary thyroid aggressiveness in terms of tumor metastasis and patients' survival.
Detailed Description: This study is a retrospective study trying to find the predictive factors for medullary thyroid aggressiveness in terms of tumor metastasis and patients' survival. The predictive factors included in this study are central and lateral compartment lymph node metastases as well as distant metastasis up to 1 year postoperatively, while biochemical predictors (meaning ratios such as lymphocyte to monocyte ratio etc and CEA and calcitonin drop levels) and histological predictors (such as nuclear atypia, amyloid, immunohistochemistry, desmoplasia) are included as secondary outcomes. In this study , patients \>18 years old that underwent surgery for medullary thyroid cancer (total thyroidectomy, completion thyroidectomy) +/- central/lateral neck dissection) will be enrolled.
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Oregon Health & Science University, Oregon, Oregon City, Oregon, United States
Department of Surgery, Saint John of God Hospital, Salzburg, Austria, Salzburg, , Austria
Saint Luc, University Clouvain, Belgium, Bruxelles, , Belgium
Head and Neck Surgery Department, Hospital Ana Nery, Santa Cruz do Sul, Brazil, Santa Cruz Do Sul, , Brazil
University Clinic of Surgery, University Hospital "Lozenec", Sofia, , Bulgaria
Chinese University of Hong Kong, Hong Kong, , China
Head and Neck Department Oncologos del Occidente, Universidad de Caldas, Manizales, Colombia, Manizales, , Colombia
the University Hospital Center Sestre milosrdnice, Zagreb, Croatia, Department of Otorhinolaryngology and Head and Neck Surgery, Zagreb, , Croatia
Head and Neck Surgery, Brest University Hospital, Brest, France, Brest, , France
The University Hospital of Poitiers, France, Poitiers, , France
Thyroid Surgery Clinic IKE, Athens, Greece, Athens, , Greece
ENT Department University Hospital of Larissa, Larissa, , Greece
Department of Surgery, General University Hospital of Patras, Patra, , Greece
Aristotle University of Thessaloniki, Thessaloníki, , Greece
Gennimatas General Hospital, Thessaloníki, , Greece
Department of ENT-Head and Neck Surgery, All India Institute of Medical Sciences, Bhubaneswar, Bhubaneswar, , India
KMCH and KMCH Comprehensive Cancer Center, Coimbatore, , India
Department of Endocrine and Breast Surgery at Sanjay Gandhi Post Graduate Institute of Medical Sciences, Madurai, , India
Department of Surgery, Maulana Azad Medical College & Lok Nayak Hospital, New Delhi, , India
Endocrine and Metabolic Surgery, Bhargav Endocrine Hospital, Vijayawada, India, Vijayawada, , India
University of Sulaimani | UNIVSUL ,Department of Surgery, Kurdistan, Erbil, , Iraq
ASL VCO - San Biagio Hospital - Domodossola (VB) - Italy, Domodossola, , Italy
Dipartimento di Scienze Chirurgiche (DISC), University of Genoa, Italy, Genoa, , Italy
Asst Santi Paolo e Carlo - Ospedale Polo Universitario San Paolo, Milan, Italy, Milan, , Italy
UOC Chirurgia Endocrina e Metabolica, Fondazione Policlinico Universitario A Gemelli IRCCS, Roma, , Italy
Department of Medical and Surgical Sciences, University of Trieste, Cattinara Teaching Hospital, Trieste, Italy, Trieste, , Italy
Department of Surgery and Oncology, Endocrine Surgery Unit, Verona University Hospital, Verona, , Italy
Hashemite University of Zarqa, Zarqa, , Jordan
Hepatobiliairy and endocrine surgery, Ibn Sina Hospital, Medical School of Medecine Rabat, Mohamed Vth University of Rabat Morocco, Marrakech, , Morocco
Division of General, Endocrine and Transplant Surgery, Medical University of Gdańsk, Gdańsk, , Poland
Surgical Oncology Clinic, Institute for Oncology and Radiology of Serbia, Medical School, University of Belgrade, Belgrad, , Serbia
Comenius University in Bratislava, Department of Paediatric Surgery, National Institute of Children's Diseases, Bratislava, , Slovakia
Department of oncological surgery, St. Elisabeth cancer Institute, Bratislava, , Slovakia
Hospital Clinic (Barcelona, Spain), Barcelona, , Spain
Universitaria de Cordoba, Córdoba, , Spain
Hospital Regional de Málaga, Málaga, , Spain
Department of General and Digestive Surgery, Division of Endocrine Surgery, Complexo Hospitalario Universitario de Vigo, Vigo, Spain, Vigo, , Spain
Bern University Hospital, Bern, , Switzerland
Geneva University Hospital, Geneva, , Switzerland
Division of Endocrinology and Metabolism Department of Medicine Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok, Thailand, Bangkok, , Thailand
Ankara University Faculty of Medicine, Department of Endocrine Surgery, Ankara, , Turkey
Acibadem MAA University, Istanbul, , Turkey
Cerrahpasa medical faculty endocrine surgery department, Istanbul, , Turkey
Department of Endocrin Pathology Unit, University of Health Sciences, Faculty of Medicine, Bakırköy Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey, Istanbul, , Turkey
Endocrine surgeon-consultant, International medical center "CITIDOCTOR", Kyiv, , Ukraine
Department of Radiology, Thien Hanh Hospital, Buon Ma Thuot, Vietnam, Việt Trì, , Vietnam
Contact Details
Name: Theodossis Papavramidis, Prof
Affiliation: 1st Propedeutic Department of Surgery, AHEPA University Hospital of Thessaloniki, Greece
Role: PRINCIPAL_INVESTIGATOR
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