Spots Global Cancer Trial Database for Flavopiridol in Treating Patients With Metastatic Malignant Melanoma
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
Trial Identification
Brief Title: Flavopiridol in Treating Patients With Metastatic Malignant Melanoma
Official Title: A Phase II Study of Flavopiridol (HMR 1275; NSC 649890) in Patients With Previously Untreated Metastatic Malignant Melanoma
Study ID: NCT00005971
Conditions
Interventions
Study Description
Brief Summary: RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of flavopiridol in treating patients who have metastatic malignant melanoma.
Detailed Description: OBJECTIVES: * Assess the efficacy of flavopiridol in patients with previously untreated metastatic malignant melanoma. * Assess the toxicity of this treatment in these patients. * Assess the time to progression, early progression rate, and response duration in these patients when treated with this regimen. OUTLINE: This is a multicenter study. Patients receive flavopiridol IV over 1 hour on days 1-3. Treatment continues every 21 days for a maximum of 6 courses in the absence of disease progression or unacceptable toxicity. Patients are followed at 4 weeks, and then every 3 months until disease progression or death. PROJECTED ACCRUAL: A total of 15-30 patients will be accrued for this study within 12-18 months.
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Tom Baker Cancer Center - Calgary, Calgary, Alberta, Canada
Lethbridge Cancer Clinic, Lethbridge, Alberta, Canada
Penticton Regional Hospital, Penticton, British Columbia, Canada
Prostate Centre at Vancouver General Hospital, Vancouver, British Columbia, Canada
St. Paul's Hospital - Vancouver, Vancouver, British Columbia, Canada
G. Steinhoff Clinical Research, Victoria, British Columbia, Canada
Moncton Hospital, Moncton, New Brunswick, Canada
Doctor Leon Richard Oncology Centre, Moncton, New Brunswick, Canada
Saint John Regional Hospital, Saint John, New Brunswick, Canada
Newfoundland Cancer Treatment and Research Foundation, St. Johns, Newfoundland and Labrador, Canada
Nova Scotia Cancer Centre, Halifax, Nova Scotia, Canada
Royal Victoria Hospital, Barrie, Barrie, Ontario, Canada
William Osler Health Centre, Brampton, Ontario, Canada
Hamilton and Disrict Urology Association, Hamilton, Ontario, Canada
London Health Sciences Centre, London, Ontario, Canada
Trillium Health Centre, Mississauga, Ontario, Canada
Credit Valley Hospital, Mississauga, Ontario, Canada
York County Hospital, Newmarket, Ontario, Canada
North York General Hospital, Ontario, North York, Ontario, Canada
Male Health Centre/CMX Research Inc., Oakville, Ontario, Canada
Lakeridge Health Oshawa, Oshawa, Ontario, Canada
Ottawa Regional Cancer Centre, Ottawa, Ontario, Canada
Peterborough Oncology Clinic, Peterborough, Ontario, Canada
Scarborough Hospital - General Site, Scarborough, Ontario, Canada
Hotel Dieu Health Sciences Hospital - Niagara, St. Catharines, Ontario, Canada
Northeastern Ontario Regional Cancer Centre, Sudbury, Sudbury, Ontario, Canada
Northwestern Ontario Regional Cancer Centre, Thunder Bay, Thunder Bay, Ontario, Canada
Toronto East General Hospital, Toronto, Ontario, Canada
Toronto Sunnybrook Regional Cancer Centre, Toronto, Ontario, Canada
St. Michael's Hospital - Toronto, Toronto, Ontario, Canada
Mount Sinai Hospital - Toronto, Toronto, Ontario, Canada
Toronto General Hospital, Toronto, Ontario, Canada
Princess Margaret Hospital, Toronto, Ontario, Canada
Women's College Campus, Sunnybrook and Women's College Health Science Center, Toronto, Ontario, Canada
Saint Joseph's Health Centre - Toronto, Toronto, Ontario, Canada
Humber River Regional Hospital, Weston, Ontario, Canada
Cancer Care Ontario - Windsor Regional Cancer Centre, Windsor, Ontario, Canada
Queen Elizabeth Hospital, PEI, Charlottetown, Prince Edward Island, Canada
CHUS-Hopital Fleurimont, Fleurimont, Quebec, Canada
Centre Hospitalier Regional de Lanaudiere, Joliette, Quebec, Canada
Maisonneuve-Rosemont Hospital, Montreal, Quebec, Canada
McGill University, Montreal, Quebec, Canada
Centre Hospitalier de l'Universite' de Montreal, Montreal, Quebec, Canada
Hotel Dieu de Montreal, Montreal, Quebec, Canada
Hopital Du Sacre-Coeur de Montreal, Montreal, Quebec, Canada
Centre Hospitalier Universitaire de Quebec, Quebec City, Quebec, Canada
Hopital du Saint-Sacrament, Quebec, Quebec City, Quebec, Canada
L'Hopital Laval, Ste-Foy, Quebec, Canada
Allan Blair Cancer Centre, Regina, Saskatchewan, Canada
Saskatoon Cancer Centre, Saskatoon, Saskatchewan, Canada
Contact Details
Name: Susan Burdette-Radoux, MD
Affiliation: McGill Cancer Centre at McGill University
Role: STUDY_CHAIR
Take Control of Your Skin and Body Changes Today.
Try out Spots for free, set up only takes 2 mins.
Join others from around the world:
