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Spots Global Cancer Trial Database for A Study of Relatlimab Plus Nivolumab Versus Nivolumab Alone in Participants With Advanced Melanoma

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Trial Identification

Brief Title: A Study of Relatlimab Plus Nivolumab Versus Nivolumab Alone in Participants With Advanced Melanoma

Official Title: A Randomized, Double-Blind Phase 2/3 Study of Relatlimab Combined With Nivolumab Versus Nivolumab in Participants With Previously Untreated Metastatic or Unresectable Melanoma

Study ID: NCT03470922

Conditions

Melanoma

Interventions

Relatlimab
Nivolumab

Study Description

Brief Summary: The purpose of this study is to determine whether relatlimab in combination with nivolumab is more effective than nivolumab by itself in treating unresectable melanoma or melanoma that has spread.

Detailed Description:

Eligibility

Minimum Age: 12 Years

Eligible Ages: CHILD, ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Local Institution - 0010, Tucson, Arizona, United States

Local Institution - 0020, Los Angeles, California, United States

Coastal Integrative Cancer Care, San Luis Obispo, California, United States

Local Institution - 0116, Santa Barbara, California, United States

Local Institution - 0012, Washington, District of Columbia, United States

Local Institution - 0013, Jacksonville, Florida, United States

Local Institution - 0117, Orlando, Florida, United States

Local Institution - 0007, Tampa, Florida, United States

Local Institution - 0038, Atlanta, Georgia, United States

Local Institution - 0016, Chicago, Illinois, United States

Local Institution - 0114, Fort Wayne, Indiana, United States

Local Institution - 0077, Baltimore, Maryland, United States

Local Institution - 0120, Baltimore, Maryland, United States

Local Institution - 0014, Boston, Massachusetts, United States

Local Institution - 0134, Boston, Massachusetts, United States

Local Institution - 0015, Ann Arbor, Michigan, United States

Local Institution - 0009, Minneapolis, Minnesota, United States

Local Institution - 0011, Rochester, Minnesota, United States

Local Institution - 0018, Charlotte, North Carolina, United States

Local Institution - 0019, Allentown, Pennsylvania, United States

Local Institution - 0076, Dallas, Texas, United States

Local Institution - 0008, Houston, Texas, United States

Local Institution - 0135, Buenos Aires, Distrito Federal, Argentina

Local Institution - 0002, Capital Federal, Distrito Federal, Argentina

Local Institution - 0004, Buenos Aires, , Argentina

Local Institution - 0005, Buenos Aires, , Argentina

Local Institution - 0003, Ciudad Autónoma De Buenos Aires, , Argentina

Local Institution - 0042, North Sydney, New South Wales, Australia

Local Institution - 0043, Waratah, New South Wales, Australia

Local Institution - 0041, Greenslopes, Queensland, Australia

Local Institution - 0045, Southport, Queensland, Australia

Local Institution - 0133, Bedford Park, South Australia, Australia

Local Institution - 0044, Murdoch, Western Australia, Australia

Local Institution - 0036, Graz, , Austria

Local Institution - 0037, Salzburg, , Austria

Local Institution - 0035, Wien, , Austria

Local Institution - 0047, Brussels, , Belgium

Local Institution - 0049, Bruxelles, , Belgium

Local Institution - 0048, Gent, , Belgium

Local Institution - 0058, Belo Horizonte, Minas Gerais, Brazil

Local Institution - 0057, Porto Alegre, RIO Grande DO SUL, Brazil

Local Institution - 0061, Porto Alegre, RIO Grande DO SUL, Brazil

Local Institution - 0073, Santa Cruz do Sul, RIO Grande DO SUL, Brazil

Local Institution - 0063, São Paulo, SAO Paulo, Brazil

Local Institution - 0059, Rio De Janiro, , Brazil

Local Institution - 0060, Sao Paulo, , Brazil

Local Institution - 0062, Sao Paulo, , Brazil

Local Institution - 0124, Halifax, Nova Scotia, Canada

Local Institution - 0068, Ottawa, Ontario, Canada

Local Institution - 0128, Toronto, Ontario, Canada

Local Institution - 0123, Montreal, Quebec, Canada

Local Institution - 0075, Montreal, Quebec, Canada

Local Institution - 0001, Santiago, Metropolitana, Chile

Local Institution - 0096, Medellín, Antioquia, Colombia

Local Institution - 0095, Bogota, , Colombia

Local Institution - 0105, Aarhus N, , Denmark

Local Institution - 0103, Herlev, , Denmark

Local Institution - 0104, Odense, , Denmark

Local Institution - 0100, Helsinki, Uusimaa, Finland

Local Institution - 0102, Oulu, , Finland

Local Institution - 0119, Tampere, , Finland

Local Institution - 0101, Turku, , Finland

Local Institution - 0084, Rennes, Ille-et-Vilaine, France

Local Institution - 0079, Amiens, Somme, France

Local Institution - 0080, Bordeaux Cedex, , France

Local Institution - 0085, Lille, , France

Local Institution - 0081, Marseille, , France

Local Institution - 0083, Paris, , France

Local Institution - 0078, Pierre-Benite, , France

Local Institution - 0082, Poitiers, , France

Local Institution - 0131, Tübingen, Baden-Württemberg, Germany

Local Institution - 0071, Quedlinburg, Sachsen-Anhalt, Germany

Local Institution - 0032, Buxtehude, , Germany

Local Institution - 0030, Erfurt, , Germany

Local Institution - 0027, Essen, , Germany

Local Institution - 0033, Hannover, , Germany

Local Institution - 0132, Heidelberg, , Germany

Local Institution - 0074, Homburg / Saar, , Germany

Local Institution - 0029, Köln, , Germany

Local Institution - 0028, Lubeck, , Germany

Local Institution - 0072, Mannheim, , Germany

Local Institution - 0034, Muenchen, , Germany

Local Institution - 0031, Wuerzburg, , Germany

Local Institution - 0064, Athens, , Greece

Local Institution - 0065, Thessaloniki, , Greece

Local Institution - 0086, Haifa, , Israel

Local Institution - 0088, Jerusalem, , Israel

Local Institution - 0087, Ramat-gan, , Israel

Local Institution - 0111, Torino, Piemonte, Italy

ASST Papa Giovanni XXIII - Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, , Italy

Local Institution - 0108, Milano, , Italy

Istituto Nazionale Tumori Fondazione Pascale, Napoli, , Italy

Istituto Oncologico Veneto IOV, Padova, , Italy

AOUS - Policlinico S.Maria Alle Scotte, Siena, , Italy

Local Institution - 0094, Zapopan, Jalisco, Mexico

Local Institution - 0091, Monterrey, Nuevo LEON, Mexico

Local Institution - 0093, Cancún, Quintana Roo, Mexico

Local Institution - 0092, Merida, Yucatan, Mexico

Local Institution - 0129, Veracruz, , Mexico

Local Institution - 0090, Dunedin, , New Zealand

Local Institution - 0125, Hamilton, , New Zealand

Local Institution - 0089, Tauranga, , New Zealand

Local Institution - 0121, Oslo, , Norway

Local Institution - 0040, Poznan, Wielkopolskie, Poland

Local Institution - 0039, Warszawa, , Poland

Local Institution - 0070, Cluj-Napoca, Cluj, Romania

Local Institution - 0066, Bucharest, , Romania

Local Institution - 0067, Craiova, , Romania

Local Institution - 0069, Iasi, , Romania

Local Institution - 0113, Krasnodar, , Russian Federation

Local Institution - 0127, Krasnoyarsk, , Russian Federation

Local Institution - 0112, Moscow, , Russian Federation

Local Institution - 0023, A Coruña, , Spain

Local Institution - 0024, Barcelona, , Spain

Local Institution - 0025, Barcelona, , Spain

Local Institution - 0026, Madrid, , Spain

Local Institution - 0021, San Sabastian Gipuzkoa, , Spain

Local Institution - 0022, Sevilla, , Spain

Local Institution - 0098, Goteborg, , Sweden

Local Institution - 0099, Lund, , Sweden

Local Institution - 0118, Solna, , Sweden

Local Institution - 0122, Uppsala, , Sweden

Local Institution - 0052, Bristol, Avon, United Kingdom

Local Institution - 0054, Glasgow, Dumfries & Galloway, United Kingdom

Local Institution - 0056, Swansea, Glamorgan, United Kingdom

Local Institution - 0051, London, Greater London, United Kingdom

Local Institution - 0126, Inverness, Inverness-shire, United Kingdom

Contact Details

Name: Bristol-Myers Squibb

Affiliation: Bristol-Myers Squibb

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

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