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Brief Title: A Study to Assess Safety of Relatlimab With Ipilimumab in Participants With Advanced Melanoma Who Progressed on Anti-Programmed Cell Death Protein 1 (Anti-PD-1) Treatment
Official Title: A Phase 1/2a Study to Evaluate the Safety, Tolerability, and Efficacy of Relatlimab Administered in Combination With Ipilimumab or Ipilimumab Alone in Participants With Unresectable or Metastatic Melanoma Who Have Progressed on Anti-PD-1 Therapy
Study ID: NCT03978611
Brief Summary: The primary purpose of this study is to characterize the safety, tolerability, and dose-limiting toxicities (DLTs) of relatlimab in combination with ipilimumab.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Local Institution - 0023, Tucson, Arizona, United States
Local Institution - 0002, Los Angeles, California, United States
Local Institution - 0005, Los Angeles, California, United States
Local Institution - 0001, Santa Monica, California, United States
Local Institution - 0015, Miami, Florida, United States
Local Institution - 0004, Chicago, Illinois, United States
Local Institution - 0003, Ann Arbor, Michigan, United States
Local Institution - 0008, Morristown, New Jersey, United States
Local Institution - 0018, Bruxelles, Brussels, Belgium
Local Institution - 0017, Antwerpen, , Belgium
Local Institution - 0016, Brussels, , Belgium
Local Institution - 0038, Bruxelles, , Belgium
Local Institution - 0044, Ottawa, Ontario, Canada
Local Institution - 0037, Erlangen, , Germany
Local Institution - 0034, Essen, , Germany
Local Institution - 0036, Gera, , Germany
Local Institution - 0035, Hannover, , Germany
Local Institution - 0033, Heidelberg, , Germany
Local Institution - 0032, Lübeck, , Germany
Local Institution - 0040, Nuremberg, , Germany
Local Institution - 0026, Barcelona, , Spain
Local Institution - 0030, Cordoba, , Spain
Local Institution - 0027, Hospitalet de Llobregat - Barcelona, , Spain
Local Institution - 0029, Madrid, , Spain
Local Institution - 0031, San Sebastian, , Spain
Local Institution - 0028, Valencia, , Spain
Name: Bristol-Myers Squibb
Affiliation: Bristol-Myers Squibb
Role: STUDY_DIRECTOR