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Spots Global Cancer Trial Database for A Study of HX008 for the Treatment of Patients With Malignant Melanoma

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Trial Identification

Brief Title: A Study of HX008 for the Treatment of Patients With Malignant Melanoma

Official Title: A Single-armed Open-labeled Phase II Study of HX008 (a Humanized Monoclonal Antibody Targeting PD-1) for the Treatment of Patients With Locally Advanced or Metastatic Melanoma Who Have Failed the Standard Treatments.

Study ID: NCT04749485

Conditions

Melanoma

Interventions

HX008

Study Description

Brief Summary: HX008 is a humanized monoclonal antibody targeting PD-1 on T cell surface, restores T cell activity, thus enhancing immune response and has potential to treat various types of tumors. In this study, the efficacy and safety of HX008 in patients with locally advanced or metastatic melanoma who have failed the standard treatments will be evaluated.

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Peking University Cancer Hospital and Research Institute, Beijing, Beijing, China

Fujian Cancer Hospital, Fuzhou, Fujian, China

The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China

The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China

Nanjing Drum Tower Hospital, Nanjing, Jiangsu, China

The first Hospital of Jilin University, Changchun, Jilin, China

Fudan Universtiy Shanghai Cancer Center, Shanghai, Shanghai, China

Shanghai Tenth People's Hospital, Shanghai, Shanghai, China

West China Hospital Sichuan Universtiy, Chengdu, Sichuan, China

The Affiliated Cancer Hospital of Xinjiang Medical University, Ürümqi, Xinjiang, China

Zhejiang University School of Medicine Sir Run Run Shaw Hospital, Hangzhou, Zhejiang, China

Contact Details

Name: Jun Guo, MD

Affiliation: Peking University Cancer Hospital and Research Institute

Role: STUDY_CHAIR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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