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Brief Title: Randomised Study to Compare the Efficacy of AZD6244 vs TMZ
Official Title: A Phase II, Multi-centre, Open-Label, Parallel Group, Randomised Study To Compare the Efficacy of AZD6244 vs Temozolomide in Patients With Unresectable AJCC Stage 3 or 4 Malignant Melanoma
Study ID: NCT00338130
Brief Summary: The primary purpose of this study is to compare the efficacy of AZD6244 (ARRY-142886) with temozolomide in patients with advanced melanoma
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Research Site, Santa Monica, California, United States
Research Site, Aurora, Colorado, United States
Research Site, Miami Beach, Florida, United States
Research Site, Niles, Illinois, United States
Research Site, Boston, Massachusetts, United States
Research Site, Buffalo, New York, United States
Research Site, New York, New York, United States
Research Site, Oklahoma City, Oklahoma, United States
Research Site, Pittsburgh, Pennsylvania, United States
Research Site, Nashville, Tennessee, United States
Research Site, Ciudad de Buenos Aires, , Argentina
Research Site, Vicente Lopez, , Argentina
Research Site, Heidelberg, , Australia
Research Site, Nedlands, , Australia
Research Site, Waratah, , Australia
Research Site, St. Pölten, , Austria
Research Site, Wien, , Austria
Research Site, Belo Horizonte, , Brazil
Research Site, Curitiba, , Brazil
Research Site, Goiânia, , Brazil
Research Site, Porto Alegre, , Brazil
Research Site, Salvador, , Brazil
Research Site, São Paulo, , Brazil
Research Site, Oshawa, Ontario, Canada
Research Site, Montreal, Quebec, Canada
Research Site, Odense, , Denmark
Research Site, Boulogne Billancourt, , France
Research Site, Nantes Cedex 1, , France
Research Site, Villejuif Cedex, , France
Research Site, Zürich, , Switzerland
Research Site, Glasgow, , United Kingdom
Research Site, London, , United Kingdom
Research Site, Oxford, , United Kingdom
Name: AZD6244 Medical Science Director, MD
Affiliation: AstraZeneca
Role: STUDY_DIRECTOR