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Brief Title: OH2 Injection in Melanoma
Official Title: To Evaluate a Phase III Study of OH2 Versus Investigator-selected Salvage Chemotherapy or Best Supportive Care in Melanoma Patients Who Had Failed Standard Therapy
Study ID: NCT05868707
Brief Summary: To evaluate the efficacy of OH2 injection in patients with unresectable or metastatic melanoma who have failed at least second-line standard therapy, using investigator-selected salvage chemotherapy or best supportive care (BSC) as controls.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Peking University Cancer Hospital, Beijing, Beijing, China
Chongqing University Cancer Hospital, Chongqing, Chongqing, China
Fujian Cancer Hosptial, Fuzhou, Fujian, China
Dermatology Hospital of Southern Medical University, Guangzhou, Guangdong, China
Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China
Guangxi Medical University Cancer Hospital, Nanning, Guangxi, China
Hainan Cancer Hospital, Haikou, Hainan, China
The Fourth Hospital of Hebei Medical University and Hebei Tumor Hospital, Shijiazhuang, Hebei, China
The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China
The Third People's Hospital of Zhengzhou, Zhengzhou, Henan, China
Hubei Cancer Hospital, Wuhan, Hubei, China
Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei, China
Hunan Cancer Hospital, Changsha, Hunan, China
Nanjing Drum Tower Hospital, Nanjing, Jiangsu, China
The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China
Jilin Cancer Hospital, Changchun, Jilin, China
The first hospital of Jilin University, Changchun, Jilin, China
The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China
Liaoning Cancer Hospital & Institute, Shenyang, Liaoning, China
The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China
The Affiliated Cancer Hospital of Shandong First Medical University, Jinan, Shandong, China
Weifang People's Hospital, Weifang, Shandong, China
Fudan University Shanghai Cancer Center, Shanghai, Shanghai, China
Shanxi Bethune Hospital, Taiyuan, Shanxi, China
West China Hospital of Sichuan University, Chengdu, Sichuan, China
Tianjin Medical University Cancer Institute & Hospital, Tianjin, Tianjin, China
The Affiliated Cancer Hospital, Xinjiang Medical University, Urumqi, Xinjiang, China
Yunnan Cancer Hospital, Kunming, Yunnan, China
Cancer Hospital Of The University Of Chinese Academy Of Sciences Zhejiang Cancer Hospital, Hangzhou, Zhejiang, China
Sir Run Run Shaw Hospital, Hangzhou, Zhejiang, China