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Spots Global Cancer Trial Database for Imatinib Mesylate in Treating Patients With Metastatic Melanoma

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Imatinib Mesylate in Treating Patients With Metastatic Melanoma

Official Title: Phase II Trial of Gleevec (Imatinib Mesylate, STI-571) in Metastatic Melanoma

Study ID: NCT00027586

Study Description

Brief Summary: RATIONALE: Imatinib mesylate may interfere with the growth of tumor cells and may be an effective treatment for metastatic melanoma. PURPOSE: Phase II trial to study the effectiveness of imatinib mesylate in treating patients who have metastatic melanoma.

Detailed Description: OBJECTIVES: * Determine the clinical activity of imatinib mesylate (STI571) in patients with metastatic melanoma. * Determine the side effects of this drug in these patients. * Correlate molecular studies with responsiveness to this drug in these patients. OUTLINE: Patients receive oral imatinib mesylate (STI571) twice daily. Treatment continues in the absence of disease progression or unacceptable toxicity. PROJECTED ACCRUAL: A total of 21-78 patients will be accrued for this study within 6-15 months.

Eligibility

Minimum Age:

Eligible Ages: CHILD, ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

University of Texas - MD Anderson Cancer Center, Houston, Texas, United States

Contact Details

Name: Kevin Kim, MD

Affiliation: M.D. Anderson Cancer Center

Role: STUDY_CHAIR

Name: Menashe Bar-Eli, PhD

Affiliation: M.D. Anderson Cancer Center

Role: STUDY_CHAIR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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