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Brief Title: Abraxane and Temodar Plus Genasense in Advanced Melanoma
Official Title: A Pilot Study of Abraxane® (Albumin-bound Paclitaxel) and Temodar® (Temozolomide) Plus Genasense® (Oblimersen Sodium) in Subjects With Advanced Melanoma ("The ATG Study").
Study ID: NCT00409383
Brief Summary: This study is designed to evaluate the safety, efficacy, pharmacokinetics, and pharmacodynamics of combination treatment with Temodar®, Genasense®, and Abraxane® in chemotherapy-naïve subjects with advanced melanoma and normal lactate dehydrogenase (LDH).
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
New York University Cancer Center, New York, New York, United States
Name: Anna C Pavlick, MD
Affiliation: NYU MEDICAL CENTER
Role: PRINCIPAL_INVESTIGATOR