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Spots Global Cancer Trial Database for Efficacy Study of Nivolumab Compared to Ipilimumab in Prevention of Recurrence of Melanoma After Complete Resection of Stage IIIb/c or Stage IV Melanoma

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Trial Identification

Brief Title: Efficacy Study of Nivolumab Compared to Ipilimumab in Prevention of Recurrence of Melanoma After Complete Resection of Stage IIIb/c or Stage IV Melanoma

Official Title: A Phase 3, Randomized, Double-blind Study of Adjuvant Immunotherapy With Nivolumab Versus Ipilimumab After Complete Resection of Stage IIIb/c or Stage IV Melanoma in Subjects Who Are at High Risk for Recurrence (CheckMate 238: CHECKpoint Pathway and nivoluMAb Clinical Trial Evaluation 238)

Study ID: NCT02388906

Conditions

Melanoma

Study Description

Brief Summary: The purpose of this study is to determine whether nivolumab is better than ipilimumab to prevent recurrence of melanoma.

Detailed Description:

Keywords

Eligibility

Minimum Age: 15 Years

Eligible Ages: CHILD, ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Local Institution - 0036, Little Rock, Arkansas, United States

Local Institution - 0117, La Jolla, California, United States

Local Institution - 0189, Los Angeles, California, United States

Local Institution - 0021, San Francisco, California, United States

Local Institution - 0006, San Francisco, California, United States

Local Institution - 0010, Aurora, Colorado, United States

Local Institution - 0004, Washington, District of Columbia, United States

Local Institution - 0012, Jacksonville, Florida, United States

Local Institution - 0019, Miami Beach, Florida, United States

Local Institution - 0030, Orlando, Florida, United States

Local Institution - 0032, Tampa, Florida, United States

Local Institution - 0016, Atlanta, Georgia, United States

Local Institution - 0106, Chicago, Illinois, United States

Local Institution - 0013, Boston, Massachusetts, United States

Local Institution - 0170, Boston, Massachusetts, United States

Local Institution - 0171, Boston, Massachusetts, United States

Local Institution - 0015, Ann Arbor, Michigan, United States

Local Institution - 0002, Fridley, Minnesota, United States

Local Institution - 0017, Saint Louis, Missouri, United States

Local Institution - 0123, Hackensack, New Jersey, United States

Local Institution - 0095, New Brunswick, New Jersey, United States

Local Institution - 0024, New York, New York, United States

Local Institution - 0033, New York, New York, United States

Local Institution - 0003, Charlotte, North Carolina, United States

Local Institution - 0025, Durham, North Carolina, United States

Local Institution - 0157, Columbus, Ohio, United States

Local Institution - 0031, Portland, Oregon, United States

Local Institution - 0029, Portland, Oregon, United States

Local Institution - 0022, Allentown, Pennsylvania, United States

Local Institution - 0001, Bethlehem, Pennsylvania, United States

Local Institution - 0026, Charleston, South Carolina, United States

Local Institution - 0014, Nashville, Tennessee, United States

Local Institution - 0005, Dallas, Texas, United States

Local Institution - 0027, Charlottesville, Virginia, United States

Local Institution - 0126, Seattle, Washington, United States

Local Institution - 0142, Capital Federal, Buenos Aires, Argentina

Local Institution - 0140, San Miguel de Tucuman, Tucuman, Argentina

Local Institution, Cordoba, , Argentina

Local Institution - 0079, Gateshead, New South Wales, Australia

Local Institution - 0080, Westmead, New South Wales, Australia

Local Institution - 0078, Wollstonecraft, New South Wales, Australia

Local Institution - 0082, Greenslopes, Queensland, Australia

Local Institution - 0083, Southport, Queensland, Australia

Local Institution - 0084, Adelaide, South Australia, Australia

Local Institution - 0075, Heidelberg, Victoria, Australia

Local Institution - 0077, Prahran, Victoria, Australia

Local Institution - 0085, Nedlands, Western Australia, Australia

Local Institution - 0081, Camperdown, , Australia

Local Institution - 0169, Graz, , Austria

Local Institution - 0168, Salzburg, , Austria

Local Institution - 0038, Brussels, , Belgium

Local Institution - 0040, Bruxelles, , Belgium

Local Institution - 0037, Gent, , Belgium

Local Institution - 0039, Leuven, , Belgium

Local Institution - 0051, Edmonton, Alberta, Canada

Local Institution - 0074, Vancouver, British Columbia, Canada

Local Institution - 0094, Toronto, Ontario, Canada

Local Institution - 0105, Montreal, Quebec, Canada

Local Institution - 0046, Quebec City, Quebec, Canada

Local Institution - 0101, Hradec Kralove, , Czechia

Local Institution - 0102, Ostrava-Poruba, , Czechia

Local Institution - 0099, Praha 1, , Czechia

Local Institution - 0100, Praha 2, , Czechia

Local Institution - 0047, Helsinki, , Finland

Local Institution - 0048, Tampere, , Finland

Local Institution - 0138, Lille, , France

Local Institution - 0135, Marseille Cedex 5, , France

Local Institution - 0134, Nantes, , France

Local Institution - 0136, Paris, , France

Local Institution - 0133, Pierre Benite, , France

Local Institution - 0137, Toulouse, , France

Local Institution - 0086, Athens, , Greece

Local Institution - 0087, Neo Faliro, , Greece

Local Institution - 0163, Budapest, , Hungary

Local Institution - 0166, Dublin 7, , Ireland

Local Institution - 0063, Dublin, , Ireland

Local Institution - 0108, Dublin, , Ireland

Local Institution - 0064, Galway, , Ireland

Local Institution - 0112, Bergamo, , Italy

Local Institution - 0116, Genova, , Italy

Local Institution - 0115, Meldola (FC), , Italy

Local Institution - 0113, Milano, , Italy

Local Institution - 0107, Napoli, , Italy

Local Institution - 0111, Padova, , Italy

Local Institution - 0114, Roma, , Italy

Local Institution - 0110, Siena, , Italy

Local Institution - 0179, Nagoya, Aichi, Japan

Local Institution - 0161, Fukuoka-shi, Fukuoka, Japan

Local Institution - 0174, Tsukuba-shi, Ibaraki, Japan

Local Institution - 0162, Kumamoto-shi, Kumamoto, Japan

Local Institution - 0160, Matsumoto, Nagano, Japan

Local Institution - 0175, Niigata-shi, Niigata, Japan

Local Institution - 0176, Osaka-shi, Osaka, Japan

Local Institution - 0159, Sunto-gun, Shizuoka, Japan

Local Institution - 0158, Chuo-ku, Tokyo, Japan

Local Institution - 0180, Chuo-shi, Yamanashi, Japan

Local Institution - 0144, Songpa-gu, Seoul, Korea, Republic of

Local Institution - 0129, Seoul, , Korea, Republic of

Local Institution - 0127, Seoul, , Korea, Republic of

Local Institution - 0128, Seoul, , Korea, Republic of

Local Institution - 0042, Amsterdam, , Netherlands

Local Institution - 0045, Groningen, , Netherlands

Local Institution - 0043, Nijmegen, , Netherlands

Local Institution - 0041, Veldhoven, , Netherlands

Local Institution - 0098, Bergen, , Norway

Local Institution - 0109, Oslo, , Norway

Local Institution - 0150, Gdansk, , Poland

Local Institution - 0149, Krakow, , Poland

Local Institution - 0152, Warszawa, , Poland

Local Institution - 0156, Craiova, , Romania

Local Institution - 0153, Romania, , Romania

Local Institution - 0148, Johannesburg, Gauteng, South Africa

Local Institution - 0145, Pretoria, Gauteng, South Africa

Local Institution - 0147, Saxonwold, Johannesburg, Gauteng, South Africa

Local Institution - 0181, Cape Town, Western CAPE, South Africa

Local Institution - 0146, Kraaifontein, Western Cape, South Africa

Local Institution - 0120, Barcelona, , Spain

Local Institution - 0119, Madrid, , Spain

Local Institution - 0121, Sevilla, , Spain

Local Institution - 0122, Valencia, , Spain

Local Institution - 0050, Gothenberg, , Sweden

Local Institution - 0096, Lund, , Sweden

Local Institution - 0167, Zuerich, , Switzerland

Local Institution - 0131, Kaohsiung, , Taiwan

Local Institution - 0132, Taichung, , Taiwan

Local Institution - 0130, Taoyuan, , Taiwan

Local Institution - 0057, Bristol, Avon, United Kingdom

Local Institution - 0052, Swansea, Carmarthenshire, United Kingdom

Local Institution - 0165, London, Greater London, United Kingdom

Local Institution - 0054, Manchester, Greater Manchester, United Kingdom

Local Institution - 0056, Southampton, Hampshire, United Kingdom

Local Institution - 0177, Northwood, Middlesex, United Kingdom

Local Institution - 0055, Oxford, Oxfordshire, United Kingdom

Local Institution - 0060, Newcastle Upon Tyne, Tyne And Wear, United Kingdom

Local Institution - 0097, Leicester, , United Kingdom

Local Institution - 0053, Surrey, , United Kingdom

Contact Details

Name: Bristol-Myers Squibb

Affiliation: Bristol-Myers Squibb

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

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