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Brief Title: Efficacy Study of Nivolumab Compared to Ipilimumab in Prevention of Recurrence of Melanoma After Complete Resection of Stage IIIb/c or Stage IV Melanoma
Official Title: A Phase 3, Randomized, Double-blind Study of Adjuvant Immunotherapy With Nivolumab Versus Ipilimumab After Complete Resection of Stage IIIb/c or Stage IV Melanoma in Subjects Who Are at High Risk for Recurrence (CheckMate 238: CHECKpoint Pathway and nivoluMAb Clinical Trial Evaluation 238)
Study ID: NCT02388906
Brief Summary: The purpose of this study is to determine whether nivolumab is better than ipilimumab to prevent recurrence of melanoma.
Detailed Description:
Minimum Age: 15 Years
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Local Institution - 0036, Little Rock, Arkansas, United States
Local Institution - 0117, La Jolla, California, United States
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Local Institution - 0021, San Francisco, California, United States
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Local Institution - 0004, Washington, District of Columbia, United States
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Local Institution - 0015, Ann Arbor, Michigan, United States
Local Institution - 0002, Fridley, Minnesota, United States
Local Institution - 0017, Saint Louis, Missouri, United States
Local Institution - 0123, Hackensack, New Jersey, United States
Local Institution - 0095, New Brunswick, New Jersey, United States
Local Institution - 0024, New York, New York, United States
Local Institution - 0033, New York, New York, United States
Local Institution - 0003, Charlotte, North Carolina, United States
Local Institution - 0025, Durham, North Carolina, United States
Local Institution - 0157, Columbus, Ohio, United States
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Local Institution - 0029, Portland, Oregon, United States
Local Institution - 0022, Allentown, Pennsylvania, United States
Local Institution - 0001, Bethlehem, Pennsylvania, United States
Local Institution - 0026, Charleston, South Carolina, United States
Local Institution - 0014, Nashville, Tennessee, United States
Local Institution - 0005, Dallas, Texas, United States
Local Institution - 0027, Charlottesville, Virginia, United States
Local Institution - 0126, Seattle, Washington, United States
Local Institution - 0142, Capital Federal, Buenos Aires, Argentina
Local Institution - 0140, San Miguel de Tucuman, Tucuman, Argentina
Local Institution, Cordoba, , Argentina
Local Institution - 0079, Gateshead, New South Wales, Australia
Local Institution - 0080, Westmead, New South Wales, Australia
Local Institution - 0078, Wollstonecraft, New South Wales, Australia
Local Institution - 0082, Greenslopes, Queensland, Australia
Local Institution - 0083, Southport, Queensland, Australia
Local Institution - 0084, Adelaide, South Australia, Australia
Local Institution - 0075, Heidelberg, Victoria, Australia
Local Institution - 0077, Prahran, Victoria, Australia
Local Institution - 0085, Nedlands, Western Australia, Australia
Local Institution - 0081, Camperdown, , Australia
Local Institution - 0169, Graz, , Austria
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Local Institution - 0105, Montreal, Quebec, Canada
Local Institution - 0046, Quebec City, Quebec, Canada
Local Institution - 0101, Hradec Kralove, , Czechia
Local Institution - 0102, Ostrava-Poruba, , Czechia
Local Institution - 0099, Praha 1, , Czechia
Local Institution - 0100, Praha 2, , Czechia
Local Institution - 0047, Helsinki, , Finland
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Local Institution - 0133, Pierre Benite, , France
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Local Institution - 0064, Galway, , Ireland
Local Institution - 0112, Bergamo, , Italy
Local Institution - 0116, Genova, , Italy
Local Institution - 0115, Meldola (FC), , Italy
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Local Institution - 0107, Napoli, , Italy
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Local Institution - 0110, Siena, , Italy
Local Institution - 0179, Nagoya, Aichi, Japan
Local Institution - 0161, Fukuoka-shi, Fukuoka, Japan
Local Institution - 0174, Tsukuba-shi, Ibaraki, Japan
Local Institution - 0162, Kumamoto-shi, Kumamoto, Japan
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Local Institution - 0175, Niigata-shi, Niigata, Japan
Local Institution - 0176, Osaka-shi, Osaka, Japan
Local Institution - 0159, Sunto-gun, Shizuoka, Japan
Local Institution - 0158, Chuo-ku, Tokyo, Japan
Local Institution - 0180, Chuo-shi, Yamanashi, Japan
Local Institution - 0144, Songpa-gu, Seoul, Korea, Republic of
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Local Institution - 0042, Amsterdam, , Netherlands
Local Institution - 0045, Groningen, , Netherlands
Local Institution - 0043, Nijmegen, , Netherlands
Local Institution - 0041, Veldhoven, , Netherlands
Local Institution - 0098, Bergen, , Norway
Local Institution - 0109, Oslo, , Norway
Local Institution - 0150, Gdansk, , Poland
Local Institution - 0149, Krakow, , Poland
Local Institution - 0152, Warszawa, , Poland
Local Institution - 0156, Craiova, , Romania
Local Institution - 0153, Romania, , Romania
Local Institution - 0148, Johannesburg, Gauteng, South Africa
Local Institution - 0145, Pretoria, Gauteng, South Africa
Local Institution - 0147, Saxonwold, Johannesburg, Gauteng, South Africa
Local Institution - 0181, Cape Town, Western CAPE, South Africa
Local Institution - 0146, Kraaifontein, Western Cape, South Africa
Local Institution - 0120, Barcelona, , Spain
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Local Institution - 0122, Valencia, , Spain
Local Institution - 0050, Gothenberg, , Sweden
Local Institution - 0096, Lund, , Sweden
Local Institution - 0167, Zuerich, , Switzerland
Local Institution - 0131, Kaohsiung, , Taiwan
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Local Institution - 0130, Taoyuan, , Taiwan
Local Institution - 0057, Bristol, Avon, United Kingdom
Local Institution - 0052, Swansea, Carmarthenshire, United Kingdom
Local Institution - 0165, London, Greater London, United Kingdom
Local Institution - 0054, Manchester, Greater Manchester, United Kingdom
Local Institution - 0056, Southampton, Hampshire, United Kingdom
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Local Institution - 0055, Oxford, Oxfordshire, United Kingdom
Local Institution - 0060, Newcastle Upon Tyne, Tyne And Wear, United Kingdom
Local Institution - 0097, Leicester, , United Kingdom
Local Institution - 0053, Surrey, , United Kingdom
Name: Bristol-Myers Squibb
Affiliation: Bristol-Myers Squibb
Role: STUDY_DIRECTOR