Spots Global Cancer Trial Database for Study of Combination Therapy With INCMGA00012 (Anti-PD-1), INCAGN02385 (Anti-LAG-3), and INCAGN02390 (Anti-TIM-3) in Participants With Select Advanced Malignancies
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Trial Identification
Brief Title: Study of Combination Therapy With INCMGA00012 (Anti-PD-1), INCAGN02385 (Anti-LAG-3), and INCAGN02390 (Anti-TIM-3) in Participants With Select Advanced Malignancies
Official Title: A Phase 1-2 Study of Combination Therapy With INCMGA00012 (Anti-PD-1), INCAGN02385 (Anti-LAG-3), and INCAGN02390 (Anti-TIM-3) in Participants With Select Advanced Malignancies
Study ID: NCT04370704
Conditions
Study Description
Brief Summary: The study will determine Recommended Phase 2 Dose for all study drugs, based on the safety and tolerability of the following combinations: INCAGN02385 + INCAGN02390 and INCAGN02385 + INCAGN02390 + INCMGA00012.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
The Angeles Clinic and Research Institute, Los Angeles, California, United States
University of Miami Sylvester Comprehensive Cancer Center, Miami, Florida, United States
H Lee Moffitt Cancer Center and Research, Tampa, Florida, United States
University of Iowa, Iowa City, Iowa, United States
Cancer Center For Blood Disorders A Division of American Oncology Partners P.A, Bethesda, Maryland, United States
Washington University, Saint Louis, Missouri, United States
John Theurer Cancer Center, Hackensack University Medical Center, Hackensack, New Jersey, United States
Nyu Langone Laura and Isaac Perlmutter Cancer Center, New York, New York, United States
Carolina Bio Oncology, Huntersville, North Carolina, United States
Penn State Hershey Cancer Institute, Hershey, Pennsylvania, United States
Hillman Cancer Center, Pittsburgh, Pennsylvania, United States
University of Washington-Seattle Cancer Care Alliance, Seattle, Washington, United States
Melanoma Institute Australia, Wollstonecraft, New South Wales, Australia
Greenslopes Private Hospital, Brisbane, Queensland, Australia
Flinders Medical Centre, Bedford Park, South Australia, Australia
Box Hill Hospital, Box Hill, Victoria, Australia
One Clinical Research, Nedlands, Western Australia, Australia
Contact Details
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