Spots Global Cancer Trial Database for Differential Risks for Melanoma: p16 and DNA Repair
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Trial Identification
Brief Title: Differential Risks for Melanoma: p16 and DNA Repair
Official Title: Differential Risks for Melanoma: p16 and DNA Repair
Study ID: NCT00615095
Study Description
Brief Summary: The goal of this study is to find out if some people are more likely to get melanoma, a form of skin cancer, than others. People respond to the environment in different ways. Some may be born with genes that make them more likely to get this type of skin cancer. Genes are made up of DNA. DNA damage is one of the first steps in developing cancer. Each person has many ways to repair normal damage to their genes. Some people may have a lower level of this repair and that may make them more likely to get cancer. Some genes are important for DNA repair. The genes we want to test are thought to affect the rate at which DNA can be repaired. We also want to find out if sun habits are related to these levels of DNA repair or genetic mutations.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: Yes
Locations
Memorial Sloan-Kettering Cancer Center, New York, New York, United States
Contact Details
Name: Irlene Orlow, PH.D., M.S.
Affiliation: Memorial Sloan Kettering Cancer Center
Role: PRINCIPAL_INVESTIGATOR
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