Spots Global Cancer Trial Database for Comparison of AZD6244 in Combination With Dacarbazine Versus (vs) Dacarbazine Alone in BRAF Mutation Positive Melanoma Patients
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Trial Identification
Brief Title: Comparison of AZD6244 in Combination With Dacarbazine Versus (vs) Dacarbazine Alone in BRAF Mutation Positive Melanoma Patients
Official Title: A Phase II, Double-blind, Randomised Study to Assess the Efficacy of AZD6244 in Combination With Dacarbazine Compared With Dacarbazine Alone in First Line Patients With BRAF Mutation Positive Advanced Cutaneous or Unknown Primary Melanoma
Study ID: NCT00936221
Conditions
Study Description
Brief Summary: To assess the efficacy in terms of overall survival of AZD6244 in combination with dacarbazine, compared with dacarbazine alone, in first line patients with BRAF mutation positive advanced cutaneous or unknown primary melanoma
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Research Site, Aurora, Colorado, United States
Research Site, Boston, Massachusetts, United States
Research Site, Belo Horizonte, , Brazil
Research Site, Ijuí, , Brazil
Research Site, Porto Alegre, , Brazil
Research Site, Sao Paulo, , Brazil
Research Site, Brno, , Czech Republic
Research Site, Novy Jicin, , Czech Republic
Research Site, Praha 2, , Czech Republic
Research Site, Lille Cedex, , France
Research Site, Marseille, , France
Research Site, Villejuif Cedex, , France
Research Site, Berlin, , Germany
Research Site, Essen, , Germany
Research Site, Hannover, , Germany
Research Site, Kiel, , Germany
Research Site, Tübingen, , Germany
Research Site, Budapest, , Hungary
Research Site, Györ, , Hungary
Research Site, Székesfehérvár, , Hungary
Research Site, Amsterdam, , Netherlands
Research Site, Nijmegen, , Netherlands
Research Site, Oslo, , Norway
Research Site, Barcelona, , Spain
Research Site, Houston, , Spain
Research Site, Málaga, , Spain
Research Site, Palma de Mallorca, , Spain
Research Site, Göteborg, , Sweden
Research Site, Malmö, , Sweden
Research Site, Stockholm, , Sweden
Research Site, Zürich, , Switzerland
Research Site, Cambridge, , United Kingdom
Research Site, Chelmsford, , United Kingdom
Research Site, London, , United Kingdom
Research Site, Manchester, , United Kingdom
Research Site, Newcastle upon Tyne, , United Kingdom
Research Site, Oxford, , United Kingdom
Research Site, Sutton, , United Kingdom
Contact Details
Name: Mark Middleton, Dr
Affiliation: Churchil Hospital, Oxford, UK
Role: PRINCIPAL_INVESTIGATOR
Name: Caroline Robert, Dr
Affiliation: Institute Gustave Roussy, France
Role: PRINCIPAL_INVESTIGATOR
Name: Ian Smith, Dr
Affiliation: AstraZeneca, Alderley Park, UK
Role: STUDY_DIRECTOR
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