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Brief Title: Statins and prOgression of Coronary atheRosclerosis in melanomA Patients Treated With chEckpoint inhibitorS
Official Title: Statins and prOgression of Coronary atheRosclerosis in melanomA Patients Treated With chEckpoint inhibitorS
Study ID: NCT05180942
Brief Summary: This study will incorporate a prospective randomised open blinded end-point trial in participants with stage 2, 3 or 4 melanoma treated with ICI to evaluate the impact of statin therapy on changes in coronary plaque burden and composition.
Detailed Description:
Minimum Age: 40 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Monash Health, Clayton, Victoria, Australia
Cabrini Health, Malvern, Victoria, Australia
Latrobe Regional Hospital, Traralgon, Victoria, Australia
Name: Stephen J Nicholls, MBBS, PhD
Affiliation: Monash University
Role: PRINCIPAL_INVESTIGATOR