Spots Global Cancer Trial Database for A Comparative Study of Prophylactic Anticoagulation in Meningioma Surgery
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Trial Identification
Brief Title: A Comparative Study of Prophylactic Anticoagulation in Meningioma Surgery
Official Title: A Comparative Study of Prophylactic Enoxaparin Routinely Administered Preoperative for Prevention of Venous Thromboembolism in Meningioma Surgery - an Acceptable Risk-benefit Ratio?
Study ID: NCT01941602
Conditions
Study Description
Brief Summary: The aim of the study is to compare different strategies for prevention of venous thromboembolism related to intracranial meningioma surgery. The investigators identified three hospitals where two have a very restrictive approach with respect to anticoagulant therapy while at the third hospital the use of anticoagulation the day before surgery was initiated as routine prophylaxis. Based on this "natural experiment" it will be explored whether the use of anticoagulant prophylaxis is associated with reduced risk of venous thromboembolism and/or associated with increased risk of postoperative hemorrhage as compared to the 2 cohorts where this intervention were absent.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
University Hospital of North Norway, Tromsø, , Norway
St Olavs Hospital, Trondheim, , Norway
Karolinska University Hospital, Stockholm, , Sweden
Contact Details
Name: Lars Jacob Stovner, MD PhD
Affiliation: St. Olavs Hospital
Role: STUDY_DIRECTOR
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