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Brief Title: Comparing Radical Surgery and Radical Radiotherapy as First Definitive Treatment for Primary MCC
Official Title: Rational-MCC: A Randomised Phase III Multi-centre Trial Comparing Radical Surgery and Radical Radiotherapy as First Definitive Treatment for Primary MCC
Study ID: NCT05253144
Brief Summary: A randomised phase III multi-centre trial comparing radical surgery and radical radiotherapy as first definitive treatment for primary MCC
Detailed Description: A randomised phase III multi-centre trial comparing radical surgery and radical radiotherapy as first definitive treatment for primary MCC with an observational study for patients ineligible for the randomised trial.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
University Hospital Birmingham NHS Foundation Trust, Birmingham, , United Kingdom
North Bristol NHS Trust, Bristol, , United Kingdom
Cambridge University Hospitals NHS Foundation Trust, Cambridge, , United Kingdom
NHS Tayside, Dundee, , United Kingdom
Barts Health NHS Trust, London, , United Kingdom
Christie NHS Foundation Trust, Manchester, , United Kingdom
Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich, , United Kingdom
Nottingham University Hospitals NHS Trust, Nottingham, , United Kingdom
Oxford University Hospitals NHS Trust, Oxford, , United Kingdom
St Helens and Knowsley Hospitals NHS Trust, Prescot, , United Kingdom
Lancashire Teaching Hospitals NHS Foundation Trust, Preston, , United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, , United Kingdom
University Hospital of North Midlands Trust, Stoke-on-Trent, , United Kingdom
Royal Cornwall Hospitals NHS Trust, Truro, , United Kingdom
Name: Neil Steven
Affiliation: University of Birmingham
Role: PRINCIPAL_INVESTIGATOR