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Brief Title: A Study to Evaluate Nivolumab in Combination With Ipilimumab Versus Pemetrexed With Cisplatin or Carboplatin for Unresectable Pleural Mesothelioma in Chinese Participants
Official Title: A Phase II, Randomized, Open-label Trial of Nivolumab in Combination With Ipilimumab Versus Pemetrexed With Cisplatin or Carboplatin as First-line Therapy for Unresectable Pleural Mesothelioma in Chinese Participants
Study ID: NCT05136677
Brief Summary: The purpose of this study is to assess the efficacy and safety of the combination of nivolumab and ipilimumab in Chinese participants with malignant pleural mesothelioma.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Local Institution - 0009, Beijing, Beijing, China
Local Institution - 0013, Harbin, Heilongjiang, China
The First Affiliated Hospital of Zhengzhou Universtiy-Oncology department, Zhengzhou, Henan, China
Local Institution - 0008, Changsha, Hunan, China
Local Institution - 0005, Changsha, Hunan, China
Local Institution - 0023, Wuhan, Hunan, China
Local Institution - 0036, Hohhot, Inner Mongolia, China
Northern Jiangsu People's Hospital-General Surgery Department, Yangzhou, Jiangsu, China
The First Hospital of Jilin University, Changchun, Jilin, China
Local Institution - 0019, Shenyang, Liaoning, China
Liaoning Cancer Hospital-Oncology, Shenyang, Liaoning, China
Local Institution - 0021, Shenyang, Liaoning, China
Local Institution - 0037, Jinan, Shandong, China
Local Institution - 0030, Qingdao, Shandong, China
Shanghai Chest Hospital, Shanghai, Shanghai, China
Local Institution - 0034, Shanghai, Shanghai, China
Local Institution - 0033, Taiyuan, Shanxi, China
Sichuan Cancer hospital, Chengdu, Sichuan, China
Tianjin Medical University General Hospital-Oncology Department, Tianjin, Tianjin, China
Tianjin Medical University Cancer Institute and Hospital-lung cancer, Tianjin, Tianjin, China
Yunnan Province Cancer Hospital, Kunming, Yunnan, China
The First Affiliated Hospital, Zhejiang University-Respiratory Department, Hangzhou, Zhejiang, China
Zhejiang Cancer Hospital-Thoracic Surgery, Hangzhou, Zhejiang, China
Local Institution - 0012, Ningbo, Zhejiang, China
Ningbo Medical Center-respiratory, Ningbo, Zhejiang, China
Name: Bristol-Myers Squibb
Affiliation: Bristol-Myers Squibb
Role: STUDY_DIRECTOR