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Spots Global Cancer Trial Database for A Phase I/Ib Study of NIZ985 in Combination With PDR001 in Adults With Metastatic Cancers

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Trial Identification

Brief Title: A Phase I/Ib Study of NIZ985 in Combination With PDR001 in Adults With Metastatic Cancers

Official Title: A Phase 1 Study of Subcutaneous Recombinant Human NIZ985 ((hetIL-15) (IL15/sIL-15Ra)) Alone and in Combination With PDR001 in Adults With Metastatic Cancers

Study ID: NCT02452268

Interventions

NIZ985
PDR001

Study Description

Brief Summary: Phase I/Ib multicenter clinical trial. Single agent dose escalation of NIZ985 followed by expansion. Second escalation of NIZ985 in combination with PDR001 followed by expansion

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

National Cancer Institute National Cancer Institute, Bethesda, Maryland, United States

Washington University School of Medicine SC, Saint Louis, Missouri, United States

The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States

Providence Portland Medical Center SC, Portland, Oregon, United States

Huntsman Cancer Institute, Salt Lake City, Utah, United States

Seattle Cancer Care Alliance, Seattle, Washington, United States

University of Wisconsin, Madison, Wisconsin, United States

Contact Details

Name: Novartis Pharmaceuticals

Affiliation: Novartis Pharmaceuticals

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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