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Spots Global Cancer Trial Database for Genomic and Proteomic Profiling Targets Influenced Treatment in Metastatic Breast Cancer

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Genomic and Proteomic Profiling Targets Influenced Treatment in Metastatic Breast Cancer

Official Title: A Two Arm Pilot Study Utilizing Molecular Profiling to Find Potential Targets and Influence Treatments for Patients With Metastatic Breast Cancer or Advanced Gynecological Malignancies

Study ID: NCT02470819

Interventions

Genetic profiling

Study Description

Brief Summary: The primary objective is to examine the impact on progression-free survival of targeted therapy for breast cancer suggested by proteomic and genomic profiling.

Detailed Description: To explore the impact of targeted therapy for breast cancer suggested by proteomic and genomic profiling using RPMA, targeted resequencing, IHC analysis, WGS, RNA-seq, and Exome sequencing on progression-free survival. When a molecular target cannot be identified, the patient will be treated with a therapy selected on an empirical basis by the investigator/treating physician at the individual site and will be followed for survival status. Only available, FDA-approved agents will be used.

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Avera Cancer Institute, Sioux Falls, South Dakota, United States

Contact Details

Name: Brian Leyland-Jones, MD

Affiliation: Avera McKennan

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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