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Brief Title: Capecitabine With Digoxin for Metastatic Breast Cancer
Official Title: Metronomic Capecitabine With Digoxin for Metastatic Breast Cancer Progressing After Anthracycline and Taxane Treatment
Study ID: NCT01887288
Brief Summary: To evaluate the Growth Modulation Index (GMI) of the combination of metronomic capecitabine with oral digoxin in metastatic breast cancer
Detailed Description: In this phase II study, the Investigators will combine metronomic capecitabine with digoxin to treat metastatic breast cancer patients who have progressed on both anthracyclines and taxanes. We hypothesize that the combination of digoxin with metronomic capecitabine may lead to increased efficacy and duration of treatment without progression with decreased side effects than standard regimen.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Western Regional Medical Center, Goodyear, Arizona, United States
Name: Jiaxin Niu, MD, PhD
Affiliation: Western Regional Medical Center
Role: PRINCIPAL_INVESTIGATOR