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Brief Title: Cediranib (AZD2171, RECENTIN™) in Addition to Chemotherapy in Patients With Untreated Metastatic Colorectal Cancer
Official Title: A Randomised, Double-blind, Phase III Study to Compare the Efficacy and Safety of Cediranib (AZD2171, RECENTIN™) When Added to 5 Fluorouracil, Leucovorin and Oxaliplatin (FOLFOX) or Capecitabine and Oxaliplatin (XELOX) With the Efficacy and Safety of Placebo When Added to FOLFOX or XELOX in Patients With Previously Untreated Metastatic Colorectal Cancer.
Study ID: NCT00399035
Brief Summary: The purpose of this study is to determine if Cediranib when added to chemotherapy is more effective than chemotherapy alone in prolonging life expectancy and slowing disease progression in patients with previously untreated metastatic colorectal cancer.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Research Site, Buenos Aires City, , Argentina
Research Site, Capital Federal, , Argentina
Research Site, Ciudad de Buenos Aires, , Argentina
Research Site, Córdoba, , Argentina
Research Site, Resistencia, , Argentina
Research Site, Rosario, , Argentina
Research Site, Santa Fe, , Argentina
Research Site, Ashford, , Australia
Research Site, Camperdown, , Australia
Research Site, Heidelberg, , Australia
Research Site, Hornsby, , Australia
Research Site, Liverpool, , Australia
Research Site, Waratah, , Australia
Research Site, Wodonga, , Australia
Research Site, Curitiba, , Brazil
Research Site, Goiânia, , Brazil
Research Site, Jaú, , Brazil
Research Site, Porto Alegre, , Brazil
Research Site, Rio de Janeiro, , Brazil
Research Site, Salvador, , Brazil
Research Site, Santo André, , Brazil
Research Site, Sao Paulo, , Brazil
Research Site, São Paulo, , Brazil
Research Site, Plovdiv, , Bulgaria
Research Site, Sofia, , Bulgaria
Research Site, Stara Zagora, , Bulgaria
Research Site, Varna, , Bulgaria
Research Site, Veliko Tarnovo, , Bulgaria
Research Site, Vratza, , Bulgaria
Research Site, Beijing, , China
Research Site, Changchun, , China
Research Site, Chengdu, , China
Research Site, ChongQing, , China
Research Site, Fuzhou, , China
Research Site, Guangzhou, , China
Research Site, Hangzhou, , China
Research Site, Nanjing, , China
Research Site, Nanning, , China
Research Site, Shanghai, , China
Research Site, Tianjin, , China
Research Site, Brno, , Czech Republic
Research Site, Ceske Budejovice, , Czech Republic
Research Site, Cheb, , Czech Republic
Research Site, Jicin, , Czech Republic
Research Site, Jihlava, , Czech Republic
Research Site, Olomouc, , Czech Republic
Research Site, Ostrava, , Czech Republic
Research Site, Praha 6, , Czech Republic
Research Site, Pribram - Zdabor, , Czech Republic
Research Site, Sumperk, , Czech Republic
Research Site, Zlin, , Czech Republic
Research Site, Znojmo, , Czech Republic
Research Site, Essen, , Germany
Research Site, Freiburg, , Germany
Research Site, Goslar, , Germany
Research Site, Hamburg, , Germany
Research Site, Hildesheim, , Germany
Research Site, Mannheim, , Germany
Research Site, Budapest, , Hungary
Research Site, Debrecen, , Hungary
Research Site, Györ, , Hungary
Research Site, Kecskemét, , Hungary
Research Site, Nyíregyháza, , Hungary
Research Site, Szombathely, , Hungary
Research Site, Zalaegerszeg, , Hungary
Research Site, Hyderabad, , India
Research Site, Trivandrum, , India
Research Site, Goyang-si, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Cebu City, , Philippines
Research Site, Davao City, , Philippines
Research Site, Iloilo, , Philippines
Research Site, Quezon City, , Philippines
Research Site, Quezon, , Philippines
Research Site, Bydgoszcz, , Poland
Research Site, Gdańsk, , Poland
Research Site, Gliwice, , Poland
Research Site, Kraków, , Poland
Research Site, Olsztyn, , Poland
Research Site, Toruń, , Poland
Research Site, Wrocław, , Poland
Research Site, Bellinzona, , Switzerland
Research Site, Lausanne, , Switzerland
Research Site, Locarno, , Switzerland
Research Site, Zürich, , Switzerland
Research Site, Tainan, , Taiwan
Research Site, Taipei, , Taiwan
Research Site, Aberdeen, , United Kingdom
Research Site, Belfast, , United Kingdom
Research Site, Leicester, , United Kingdom
Research Site, Manchester, , United Kingdom
Name: Jane Robertson
Affiliation: AstraZeneca
Role: STUDY_DIRECTOR