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Spots Global Cancer Trial Database for Efficacy and Safety of the Prophylactic Use of Doxycycline +/- Vitamin K Cream

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Trial Identification

Brief Title: Efficacy and Safety of the Prophylactic Use of Doxycycline +/- Vitamin K Cream

Official Title: A Double Blind Placebo Controlled Randomized Phase II Study Evaluating the Efficacy and Safety of the Prophylactic Use of Doxycycline +/- Vitamin K Cream in First Line mCRC Patients Treated With Erbitux and FOLFIRI.

Study ID: NCT01345526

Study Description

Brief Summary: The aim of this Phase 2, two-arm, randomized, double blind placebo controlled study is to evaluate the efficacy of combination therapy of doxycycline and Vitamin K1 compared to doxycycline plus placebo for the prevention of acne-like skin rash in mCRC patients receiving first line cetuximab treatment.

Detailed Description: The aim of this Phase 2, two-arm, randomized, double blind placebo controlled study is to evaluate the efficacy of combination therapy of doxycycline and Vitamin K1 compared to doxycycline plus placebo for the prevention of acne-like skin rash in mCRC patients receiving first line cetuximab treatment.

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Unversity Hospital Mannheim, Mannheim, , Germany

Institute of Oncology Ljubljana, Ljubljana, , Slovenia

Contact Details

Name: Ralf Hofheinz, Prof.

Affiliation: Universitätsmedizin Mannheim

Role: STUDY_CHAIR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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