Spots Global Cancer Trial Database for FOLFOXIRI With or Without Panitumumab in Metastatic Colorectal Cancer (VOLFI)
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Trial Identification
Brief Title: FOLFOXIRI With or Without Panitumumab in Metastatic Colorectal Cancer (VOLFI)
Official Title: An Open-label 2:1 Randomized Phase II Study of Panitumumab Plus FOLFOXIRI or FOLFOXIRI Alone as First-line Treatment of Patients With Non-resectable Metastatic Colorectal Cancer and RAS Wild Type
Study ID: NCT01328171
Conditions
Study Description
Brief Summary: The aim of the trial is to optimize response rates and rates of secondary resections of metastases in patients with initially non-resectable metastatic colorectal cancer of RAS wildtype. The patients will be treated in two therapy groups: Experimental arm A: Chemotherapy with FOLFOXIRI + panitumumab Standard arm B: Chemotherapy with FOLFOXIRI
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Klinikum Esslingen, Esslingen, Baden-Württemberg, Germany
SLK-Kliniken Heilbronn GmbH, Heilbronn, Baden-Württemberg, Germany
Ortenau Klinikum, Lahr, Baden-Württemberg, Germany
Klinikum Ludwigsburg, Ludwigsburg, Baden-Württemberg, Germany
Universitätsklinikum Mannheim, Mannheim, Baden-Württemberg, Germany
Klinikum Schwäbisch Gmünd, Mutlangen, Baden-Württemberg, Germany
Kreiskliniken Esslingen gGmbH Klinik Nürtingen, Nürtingen, Baden-Württemberg, Germany
Schwerpunktpraxis und Tagesklinik Onkologie Hämatologie Gastroenterologie Palliativmedizin Drs. Höring, Respondek, Schwinger, Thunert, Stuttgart, Baden-Württemberg, Germany
Universitätsklinikum Ulm Zentrum für Innere Medizin, Ulm, Baden-Württemberg, Germany
Klinikum Augsburg, Augsburg, Bayern, Germany
Leopoldina-Krankenhaus der Stadt Schweinfurth gGmbH, Schweinfurt, Bayern, Germany
Klinikum der J.W. Goethe-Universität Frankfurt, Frankfurt, Hessen, Germany
Universitätsklinikum Gießen und Marburg GmbH, Marburg, Hessen, Germany
Franziskus Hospital Niels-Stensen-Kliniken Klinik für Internistische Onkologie und Hämatologie, Georgsmarienhütte, Niedersachsen, Germany
Marienhospital Osnabrück Niels-Stensen-Kliniken Klinik für Innere Medizin, Osnabrück, Niedersachsen, Germany
St. Vincenz-Krankenhaus, Paderborn, Nordrhein-Westfalen, Germany
Klinikum Mutterhaus der Borromäerinnen gGmbH, Trier, Rheinland-Pfalz, Germany
Universitätsklinikum Halle, Halle, Sachsen-Anhalt, Germany
Universitätsklinikum Jena, Jena, Thüringen, Germany
Contact Details
Name: Michael Geißler, MD, PhD
Affiliation: Department of Oncology and Gastroenterology, Academic Teaching Hospital Esslingen
Role: PRINCIPAL_INVESTIGATOR
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