Spots Global Cancer Trial Database for Sulfasalazine in Patients With Metastatic Colorectal Cancer
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Trial Identification
Brief Title: Sulfasalazine in Patients With Metastatic Colorectal Cancer
Official Title: Clinical Study Evaluating the Efficacy and Safety of Sulfasalazine in Patients With Metastatic Colorectal Cancer
Study ID: NCT06134388
Conditions
Interventions
Study Description
Brief Summary: The aim of this study is to evaluate the potential efficacy and safety of sulfasalazine in patients with metastatic colorectal cancer.
Detailed Description: Sulfasalazine is an anti-inflammatory drug that is indicated for treatment of ulcerative colitis and rheumatoid arthritis. Sulfasalazine decreased the risk of ulcerative colitis-related colorectal cancer through its anti-inflammatory effect and induction of oxidative stress in cancer cells. Furthermore, intact sulfasalazine, but not its metabolites, inhibited the growth and metastasis various cancers.
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Tanta University Hospital, Tanta, El-Gharbia Governorate, Egypt
Contact Details
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