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Brief Title: Early-Line Anti-EGFR Therapy to Facilitate Retreatment for Select Patients With mCRC
Official Title: Phase II Trial of Early-Line Anti-EGFR Therapy to Facilitate Retreatment for Select Patients With Metastatic Colorectal Cancer
Study ID: NCT04587128
Brief Summary: The study will use previously established doses of panitumumab or cetuximab in the metastatic setting for the treatment of unresectable colorectal cancer (CRC). It is designed to investigate an alternative treatment strategy to maximize the benefit to inhibition of epidermal growth factor receptor (EGFR) for a highly selected patient population. It will enroll 71 participants with left-sided, unresectable metastatic CRC. Participants will be on study up to 5 years.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
University of Wisconsin Carbone Cancer Center, Madison, Wisconsin, United States
Name: Dustin Deming, MD
Affiliation: University of Wisconsin, Madison
Role: PRINCIPAL_INVESTIGATOR