Spots Global Cancer Trial Database for Induction Chemoterapy With Folfoxiri Plus Cetuxumab in Unresectable Colorectal Cancer Patient
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Trial Identification
Brief Title: Induction Chemoterapy With Folfoxiri Plus Cetuxumab in Unresectable Colorectal Cancer Patient
Official Title: Induction Chemotherapy With Folfoxiri Plus Cetuximab and Maintenance With Cetuximab or Bevacizumab Therapy in Unresectable Kras Wild-type Metastatic Colorectal Cancer Patients
Study ID: NCT02295930
Conditions
Study Description
Brief Summary: This is a phase II randomized study of 4-months induction first-line chemotherapy with FOLFOXIRI + cetuximab followed by maintenance with cetuximab or bevacizumab in patients affected by KRAS wild type (wt) mCRC.
Detailed Description: The aim of the study is to obtain a rapid disease control with the therapy and the maximum tumoral shrinkage, and than to treat patient with less intensive maintenance to inhibit tumoral regrowth.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Ospedale Civile Ss. Antonio E Biagio Di Alessandria - Alessandria (Al) Oncologia Medica, Alessandria, , Italy
Irccs Centro Di Riferimento Oncologico (Cro) - Aviano (Pn), Aviano, , Italy
A.O.Universitaria Policlinico S.Orsola-Malpighi Di Bologna (Oncologia Medica), Bologna, , Italy
Istituto Ospedaliero Fondazione Poliambulanza Di Brescia - Brescia (Bs) Oncologia Medica, Brescia, , Italy
Pres.Ospedal.Spedali Civili Brescia - Brescia (Bs) Oncologia Medic, Brescia, , Italy
Ospedale Armando Businco - Cagliari (Ca) Oncologia Medica, Cagliari, , Italy
Azienza Ospedaliera S. Croce E Carle, Cuneo, , Italy
AUSL DI FROSINONE - FROSINONE (FR) ONCOLOGIA MEDICA U.O. Oncologia Medica, Frosinone, , Italy
IRCCS ISTITUTO NAZIONALE PER LA RICERCA SUL CANCRO (IST) - GENOVA (GE) ONCOLOGIA MEDICA Oncologia Medica A, Genova, , Italy
Ausl 12 Di Viareggio (Lu) - Lido Di Camaiore (Lu) Oncologia Medica, Lucca, , Italy
Irccs Istituto Oncologico Veneto (Iov) - Padova (Pd) Oncologia Medica, Padova, , Italy
AZIENDA OSPEDALIERA DI PERUGIA - OSPEDALE S. MARIA DELLA MISERICORDIA - PERUGIA (PG) ONCOLOGIA MEDICA U.O. Oncologia Medica, Perugia, , Italy
Polo Oncologico Area Vasta Nord Ovest, Pisa, , Italy
AUSL 5 DI PISA - PISA (PI) ONCOLOGIA MEDICA oncologia medica Osp Lotti Pontedera, Pontedera, , Italy
Ospedale Di S. Maria Nuova - Reggio Nell'Emilia (Re) Oncologia Medica, Reggio Emilia, , Italy
Policlinico Universitario Campus Bio-Medico Di Roma - Roma (Rm) Oncologia Medica, Roma, , Italy
POLICLINICO UMBERTO I DI ROMA - ROMA (RM) ONCOLOGIA MEDICA oncologia Medica, Roma, , Italy
Ospedale Fatebenefratelli, Roma, , Italy
Ospedale San Pietro Fatebenefratelli - Roma (Rm) Oncologia Medica, Roma, , Italy
Ospedale Civile Di Sondrio, Sondrio, , Italy
A.O. Universitaria S. Giovanni Battista-Molinette Di Torino - Torino (to) Oncologia Medica, Torino, , Italy
A.O. UNIVERSITARIA S. MARIA DELLA MISERICORDIA DI UDINE - UDINE (UD) ONCOLOGIA MEDICA U.O. Oncologia Medica, Udine, , Italy
Contact Details
Name: Alfredo Falcone, MD
Affiliation: Polo Oncologico Area Vasta Nord Ovest
Role: PRINCIPAL_INVESTIGATOR
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