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Brief Title: Surgical Versus Nonoperative Treatment of Metastatic Epidural Spinal Cord Compression
Official Title: Surgical Versus Nonoperative Treatment of Metastatic Epidural Spinal Cord Compression. Quality of Life and Cost-effectiveness Outcomes
Study ID: NCT00634426
Brief Summary: The aim of this trial is to evaluate the differences in pain relief, neurological function, quality of life and survival in patients with metastatic epidural spinal cord compression (MESCC) who are managed with a combination of surgery and radiotherapy versus radiotherapy alone. Further we shall evaluate cost-effectiveness of the two treatment approaches.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
University of Kansas Medical Center, Kansas City, Kansas, United States
Johns Hopkins University, Baltimore, Maryland, United States
Mayo Clinic, Rochester, Minnesota, United States
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States
Thomas Jefferson University and The Rothman Institute, Philadelphia, Pennsylvania, United States
University of Texas Hospital / MD Anderson Cancer Center, Houston, Texas, United States
West Viginia University, Morgantown, West Virginia, United States
University of British Columbia, Vancouver, British Columbia, Canada
Sunnybrook Health Sciences Center, Toronto, Ontario, Canada
University of Toronto, Toronto, Ontario, Canada
Name: Michael Fehlings, MD FRCSC
Affiliation: University of Toronto
Role: PRINCIPAL_INVESTIGATOR