Spots Global Cancer Trial Database for Efficacy and Safety Trial of ADU-S100 and Pembrolizumab in Head and Neck Cancer
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Trial Identification
Brief Title: Efficacy and Safety Trial of ADU-S100 and Pembrolizumab in Head and Neck Cancer
Official Title: A Phase 2 Efficacy and Safety Trial of ADU-S100 and Pembrolizumab in Adults With Head and Neck Cancer
Study ID: NCT03937141
Interventions
Study Description
Brief Summary: ADU-CL-20 is an open-label, multicenter Phase 2 clinical trial to evaluate the efficacy and safety of intratumoral ADU-S100 (also referred to as MIW815) administered with pembrolizumab in the first-line setting. The population will consist of adults with PD-L1 positive recurrent or metastatic HNSCC.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
University of Alabama Comprehensive Cancer Center, Birmingham, Alabama, United States
University of Arizona Cancer Center, Tucson, Arizona, United States
UC San Diego Moores Cancer Center, La Jolla, California, United States
Yale University Cancer Center, New Haven, Connecticut, United States
Moffitt Cancer Center, Tampa, Florida, United States
Emory University Hospital, Atlanta, Georgia, United States
University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States
University of Kansas, Westwood, Kansas, United States
James Graham Brown Cancer Center, Louisville, Kentucky, United States
University of Maryland, Greenebaum Comprehensive Cancer Center, Baltimore, Maryland, United States
Karmanos Cancer Institute, Detroit, Michigan, United States
Regions Cancer Care Center, Saint Paul, Minnesota, United States
Washington University School of Medicine, Saint Louis, Missouri, United States
University Pittsburgh Medical Center Hillman Cancer Center, Pittsburgh, Pennsylvania, United States
MUSC Hollings Cancer Center, Charleston, South Carolina, United States
Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, United States
Baylor University Medical Center, Dallas, Texas, United States
Contact Details
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