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Spots Global Cancer Trial Database for RAD001 Plus Bevacizumab in Metastatic Melanoma

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: RAD001 Plus Bevacizumab in Metastatic Melanoma

Official Title: A Phase II Trial of RAD001 Plus Bevacizumab in the Treatment of Patients With Metastatic Melanoma

Study ID: NCT00591734

Study Description

Brief Summary: This is a non-randomized, open label Phase II study comparing bevacizumab and everolimus in the treatment of metastatic melanoma.

Detailed Description: All patients will begin treatment with the same doses of RAD001 and bevacizumab. Patients will receive 6 weeks of treatment, followed by re evaluation. Patients with objective response or stable disease will continue treatment until disease progression. During the study, all patients will receive 10 mg of RAD001 orally daily and 15 mg/kg of bevacizumab intravenously (IV) once every 3 weeks. Fifty-five patients will be enrolled in this multi-centered study

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Florida Cancer Specialists, Fort Myers, Florida, United States

Watson Clinic Center for Cancer Care and Research, Lakeland, Florida, United States

Florida Hospital Cancer Institute, Orlando, Florida, United States

Gulfcoast Oncology Associates, Saint Petersburg, Florida, United States

Northeast Georgia Medical Center, Gainesville, Georgia, United States

Oncology Hematology Associates of SW Indiana, Evansville, Indiana, United States

Center for Cancer and Blood Disorders, Bethesda, Maryland, United States

Grand Rapids Clinical Oncology Program, Grand Rapids, Michigan, United States

St. Louis Cancer Care, Chesterfield, Missouri, United States

Methodist Cancer Center, Omaha, Nebraska, United States

Consultants in Medical Oncology and Hematology, Drexel Hill, Pennsylvania, United States

Chattanooga Oncology & Hematology Associates, Chattanooga, Tennessee, United States

Tennessee Oncology, PLLC, Nashville, Tennessee, United States

South Texas Oncology and Hematology, San Antonio, Texas, United States

Virginia Cancer Institute, Richmond, Virginia, United States

Contact Details

Name: John D. Hainsworth, M.D.

Affiliation: SCRI Development Innovations, LLC

Role: STUDY_CHAIR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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