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Brief Title: PARTNER: Panitumumab Added to Regimen for Treatment of Head aNd Neck Cancer Evaluation of Response
Official Title: A Randomized, Open-Label, Controlled, Phase II Trial of Combination Chemotherapy With or Without Panitumumab as First-line Treatment of Subjects With Metastatic or Recurrent Head and Neck Cancer, and Cross-over Second-line Panitumumab Monotherapy of Subjects Who Fail the Combination Chemotherapy…
Study ID: NCT00454779
Brief Summary: This is a randomized, open-label, 2-arm, controlled, phase 2, multi-center, estimation clinical trial of docetaxel and cisplatin combination chemotherapy with and without panitumumab in the first-line treatment of subjects with metastatic or recurrent head and neck cancer, as well as a cross-over second-line panitumumab monotherapy of subjects who fail the chemotherapy only arm. This study will be conducted in the United States. Approximately 150 subjects with histologically or cytologically confirmed metastatic and/or recurrent SCCHN.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Research Site, Tucson, Arizona, United States
Research Site, Jonesboro, Arkansas, United States
Research Site, Duarte, California, United States
Research Site, La Jolla, California, United States
Research Site, La Verne, California, United States
Research Site, Los Angeles, California, United States
Research Site, Santa Cruz, California, United States
Research Site, Aurora, Colorado, United States
Research Site, Denver, Colorado, United States
Research Site, Norwich, Connecticut, United States
Research Site, Newark, Delaware, United States
Research Site, Washington, District of Columbia, United States
Research Site, Washington, District of Columbia, United States
Research Site, Washington, District of Columbia, United States
Research Site, Washington, District of Columbia, United States
Research Site, Lakeland, Florida, United States
Research Site, Miami, Florida, United States
Research Site, New Port Richey, Florida, United States
Research Site, Orlando, Florida, United States
Research Site, Athens, Georgia, United States
Research Site, Griffin, Georgia, United States
Research Site, Marietta, Georgia, United States
Research Site, Centralia, Illinois, United States
Research Site, Elk Grove Village, Illinois, United States
Research Site, Evanston, Illinois, United States
Research Site, Park Ridge, Illinois, United States
Research Site, Zion, Illinois, United States
Research Site, Wichita, Kansas, United States
Research Site, Ashland, Kentucky, United States
Research Site, Lexington, Kentucky, United States
Research Site, Louisville, Kentucky, United States
Research Site, Louisville, Kentucky, United States
Research Site, Paducah, Kentucky, United States
Research Site, Baltimore, Maryland, United States
Research Site, Baltimore, Maryland, United States
Research Site, Frederick, Maryland, United States
Research Site, Boston, Massachusetts, United States
Research Site, Ann Arbor, Michigan, United States
Research Site, Lansing, Michigan, United States
Research Site, Pascagoula, Mississippi, United States
Research Site, Columbia, Missouri, United States
Research Site, Jefferson City, Missouri, United States
Research Site, Saint Louis, Missouri, United States
Research Site, Saint Louis, Missouri, United States
Research Site, Billings, Montana, United States
Research Site, Omaha, Nebraska, United States
Research Site, Henderson, Nevada, United States
Research Site, Hackensack, New Jersey, United States
Research Site, Binghamton, New York, United States
Research Site, Bronx, New York, United States
Research Site, Bronx, New York, United States
Research Site, Mineola, New York, United States
Research Site, New York, New York, United States
Research Site, New York, New York, United States
Research Site, Nyack, New York, United States
Research Site, Rochester, New York, United States
Research Site, Syracuse, New York, United States
Research Site, Canton, Ohio, United States
Research Site, Cincinnati, Ohio, United States
Research Site, Dayton, Ohio, United States
Research Site, Toledo, Ohio, United States
Research Site, Oklahoma City, Oklahoma, United States
Research Site, Langhorne, Pennsylvania, United States
Research Site, Philadelphia, Pennsylvania, United States
Research Site, Scranton, Pennsylvania, United States
Research Site, Charleston, South Carolina, United States
Research Site, Charleston, South Carolina, United States
Research Site, Greenville, South Carolina, United States
Research Site, Memphis, Tennessee, United States
Research Site, Arlington, Texas, United States
Research Site, Corpus Christi, Texas, United States
Research Site, Corpus Christi, Texas, United States
Research Site, Dallas, Texas, United States
Research Site, Dallas, Texas, United States
Research Site, Dallas, Texas, United States
Research Site, Galveston, Texas, United States
Research Site, San Antonio, Texas, United States
Research Site, Abingdon, Virginia, United States
Research Site, Chesapeake, Virginia, United States
Research Site, Morgantown, West Virginia, United States
Research Site, Madison, Wisconsin, United States
Research Site, Marshfield, Wisconsin, United States
Research Site, Graz, , Austria
Research Site, Leoben, , Austria
Research Site, Linz, , Austria
Research Site, Wien, , Austria
Research Site, Brasschaat, , Belgium
Research Site, Brugge, , Belgium
Research Site, Kortrijk, , Belgium
Research Site, Libramont, , Belgium
Research Site, Liege, , Belgium
Research Site, Ottignies, , Belgium
Research Site, Wilrijk, , Belgium
Research Site, Brno, , Czechia
Research Site, Praha 5, , Czechia
Research Site, Znojmo, , Czechia
Research Site, Angers, , France
Research Site, Lens cedex, , France
Research Site, Perpignan, , France
Research Site, Vandoeuvre les Nancy, , France
Research Site, Kaunas, , Lithuania
Research Site, Vilnius, , Lithuania
Research Site, San Juan, , Puerto Rico
Research Site, Banska Bystrica, , Slovakia
Research Site, Bratislava, , Slovakia
Research Site, Nove Zamky, , Slovakia
Research Site, Presov, , Slovakia
Research Site, Spisska Nova Ves, , Slovakia
Research Site, Santander, Cantabria, Spain
Research Site, Barcelona, Cataluña, Spain
Research Site, Girona, Cataluña, Spain
Research Site, L Hospitalet De Llobregat, Cataluña, Spain
Research Site, Valencia, Comunidad Valenciana, Spain
Research Site, Madrid, , Spain
Name: MD
Affiliation: Amgen
Role: STUDY_DIRECTOR