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Brief Title: Study of MM-398 With or Without 5-FU/LV, Versus 5-FU/LV in Patients With Metastatic Pancreatic Cancer
Official Title: A Randomized, Open Label Phase 3 Study of MM-398, With or Without 5-Fluorouracil and Leucovorin, Versus 5 Fluorouracil and Leucovorin in Patients With Metastatic Pancreatic Cancer Who Have Failed Prior Gemcitabine-based Therapy
Study ID: NCT01494506
Brief Summary: The study is an open label, randomized phase 3 study of MM-398 with or without 5-Fluorouracil (5-FU) and Leucovorin (also known as folinic acid), versus 5-FU and leucovorin in metastatic pancreatic cancer patients who have progressed on prior gemcitabine based therapy.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
, Gilbert, Arizona, United States
, Glendale, Arizona, United States
, Scottsdale, Arizona, United States
, Burbank, California, United States
, Duarte, California, United States
, Fresno, California, United States
, LaVerne, California, United States
, San Luis Obispo, California, United States
, Boyton Beach, Florida, United States
, Atlanta, Georgia, United States
, Kansas City, Missouri, United States
, St Louis, Missouri, United States
, Henderson, Nevada, United States
, Albuquerque, New Mexico, United States
, Buffalo, New York, United States
, Columbus, Ohio, United States
, Norman, Oklahoma, United States
, Greenville, South Carolina, United States
, Bedford, Texas, United States
, Dallas, Texas, United States
, Tyler, Texas, United States
, Fairfax, Virginia, United States
, Norfolk, Virginia, United States
, Buenos Aires, , Argentina
, Rosario, , Argentina
, Santa Fe, , Argentina
, Westmead, New South Wales, Australia
, Kurralta Park, South Australia, Australia
, Boxhill, Victoria, Australia
, Heidelberg, Victoria, Australia
, Melbourne, Victoria, Australia
, Nedlands, Western Australia, Australia
, Belo Horizonte, , Brazil
, Ijui, , Brazil
, Passo Fundo, , Brazil
, Porto Alegre, , Brazil
, Sao Paulo, , Brazil
, Montreal, Quebec, Canada
, Horovice, , Czech Republic
, Olomouc, , Czech Republic
, Prague, , Czech Republic
, Pribram, , Czech Republic
, Bordeaux, , France
, Lille, , France
, Marseille, , France
, Berlin, , Germany
, Jens, , Germany
, Munich, , Germany
, Ulm, , Germany
, Budapest, , Hungary
, Pecs, , Hungary
, Szeged, , Hungary
, Szolnok, , Hungary
, Szombathely, , Hungary
, Castellana Grotte, , Italy
, Genova, , Italy
, Legnano, , Italy
, Naples, , Italy
, Roma, , Italy
, Hwasun-gun, , Korea, Republic of
, Seoul, , Korea, Republic of
, Port Elizabeth, , South Africa
, Pretoria, , South Africa
, Western Cape, , South Africa
, Alicante, , Spain
, Barcelona, , Spain
, Madrid, , Spain
, Santander, , Spain
, Valencia, , Spain
, Chiayi, , Taiwan
, Kaohsiung, , Taiwan
, Taiching, , Taiwan
, Tainan, , Taiwan
, Taipei, , Taiwan
, Taoyuan, , Taiwan
, Liverpool, , United Kingdom
, London, , United Kingdom
, Manchester, , United Kingdom
, Sutton, , United Kingdom
Name: Eliel Bayever, MD
Affiliation: Merrimack Pharmaceuticals
Role: STUDY_DIRECTOR