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Brief Title: Study of Effect of Azeliragon in Patients Refractory to First-Line Metastatic Pancreatic Cancer
Official Title: A Phase I/II Open Label Study to Assess Safety and Preliminary Evidence of a Therapeutic Effect of Azeliragon in Patients Refractory to First-Line Treatment of Metastatic Pancreatic Cancer
Study ID: NCT05766748
Brief Summary: This is an open label study to determine the safety and preliminary evidence of a therapeutic effect of azeliragon in patients refractory to first-line or second-line treatment of metastatic pancreatic cancer.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Cedars-Sinai Medical Center, Samuel Oschin Comprehensive Cancer Institute, Los Angeles, California, United States
Boca Raton Regional Hospital, Lynn Cancer Institute, Boca Raton, Florida, United States
Williamette Valley Cancer Institute and Research Center, Eugene, Oregon, United States
AHN Cancer Institute - Allegheny General Hospital, Pittsburgh, Pennsylvania, United States
Prisma Health - Upstate, Greenville, South Carolina, United States
Texas Oncology - Northeast Texas, Tyler, Texas, United States
Name: Andrew Hendifar, MD
Affiliation: Cedars-Sinai Medical Center, Samuel Oschin Comprehensive Cancer Institute
Role: PRINCIPAL_INVESTIGATOR