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Brief Title: Trial of Gemcitabine With or Without Bavituximab in Patients With Previously Untreated Stage IV Pancreatic Cancer
Official Title: A Randomized, Open-Label, Phase 2 Trial of Gemcitabine With or Without Bavituximab in Patients With Previously Untreated Stage IV Pancreatic Cancer
Study ID: NCT01272791
Brief Summary: The primary objective of this study is to compare the overall survival of patients with stage IV pancreatic cancer treated with gemcitabine alone or gemcitabine with bavituximab.
Detailed Description: This is prospective, randomized, open-label, multicenter, phase 2 study of gemcitabine with or without bavituximab in patients with previously untreated stage IV pancreatic cancer.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Ironwood Cancer & Research Centers, Chandler, Arizona, United States
Moores UCSD Cancer Center, La Jolla, California, United States
Lynn Cancer Institute, Boca Raton, Florida, United States
John B. Amos Cancer Center, Columbus, Georgia, United States
The Cancer Center at DeKalb Medical, Decatur, Georgia, United States
Northeast Georgia Medical Center, Gainesville, Georgia, United States
Nancy N. and J.C. Lewis Cancer & Research Pavilion at St. Joseph's/Candler, Savannah, Georgia, United States
Joliet Oncology-Hematology Associates, Ltd., Joliet, Illinois, United States
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, United States
Arena Oncology Associates, PC, Lake Success, New York, United States
Leo W. Jenkins Cancer Center - East Carolina University, Greenville, North Carolina, United States
St. Luke's Cancer Center, Bethlehem, Pennsylvania, United States
Vasicek Cancer Center at Scott & White Memorial Hospital, Temple, Texas, United States
Lynchburg Hematology-Oncology Clinic, Lynchburg, Virginia, United States
Municipal Institution "Cherkasy Regional Oncology Dispensary" of Cherkasy Regional Council, Cherkasy, , Ukraine
City Multi-field Clinical Hospital, Dnipropetrovsk, , Ukraine
Municipal Institution of Health Care "Kharkiv Regional Clinical Oncology Center", Kharkiv, , Ukraine
Kyiv City Oncology Center, Kyiv, , Ukraine
Name: Thomas Sklenar
Affiliation: Peregrine Pharmaceuticals
Role: STUDY_CHAIR