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Brief Title: Efficacy and Safety of Aldoxorubicin Compared to Topotecan in Subjects With Metastatic Small Cell Lung Cancer
Official Title: A Multicenter, Randomized, Open-Label Phase 2b Study to Investigate the Efficacy and Safety of Aldoxorubicin Compared to Topotecan in Subjects With Metastatic Small Cell Lung Cancer Who Either Relapsed or Were Refractory to Prior Chemotherapy
Study ID: NCT02200757
Brief Summary: The purpose of this study is to evaluate the efficacy and safety of aldoxorubicin compared to topotecan in subjects with metastatic small cell lung cancer.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Cedars-Sinai Medical Center, Los Angeles, California, United States
City of Hope Medical Group, Pasadena, California, United States
University of Colorado Cancer Center, Aurora, Colorado, United States
Lynn Cancer Institute, Boca Raton, Florida, United States
Cancer Specialists of North Florida-Fleming Island, Fleming Island, Florida, United States
Hematoloy Oncology Associates, Port St. Lucie, Florida, United States
Northwest Georgia Oncology Centers, P.C., Marietta, Georgia, United States
James Graham Brown Cancer Center, Louisville, Kentucky, United States
West Jefferson Medical Center, Cancer Center, Marrero, Louisiana, United States
Bay Hematology Oncology, Easton, Maryland, United States
Washington University School of Medicine, Department of Internal Medicine, St. Louis, Missouri, United States
Montefiore Medical Center, Bronx, New York, United States
Oncology Hermatology Care, Inc., Cincinnati, Ohio, United States
Northwest CCOP Kaiser Permanente, Portland, Oregon, United States
Penn State Hershey Cancer Institute, Hershey, Pennsylvania, United States
Tennessee Oncology, Cattanooga, Tennessee, United States
Tennessee Cancer Specialists, Knoxville, Tennessee, United States
Sarah Cannon Research Institute, Nashville, Tennessee, United States
Sarah Cannon Research Institute, Nashville, Tennessee, United States
Koranyi National Institute of TBC and Pulmonologyhhy, Budapest, , Hungary
Koranyi National Institute of TBC and Pulmonology, Budapest, , Hungary
University of Debrecen, Medical and Health Science Center, Department of Pulmonology, Debrecen, , Hungary
Szabolcs-Szatmar-Bereg County Hospitals and University Teaching Hospital, Department of Pulmonology, Nyiregyhaza, , Hungary
Medical Center of the University of Pecs, 1st Department of Internal Medicine, Pecs, , Hungary
Hetenyi Geza Hospital, Szolnok, Jasz-Nagykun-Szolnok, , Hungary
Hospital General Universitario de Alicante, Alicante, , Spain
Hospital Clinic i Provincial de Barcelona, Barcelona, , Spain
Hospital Universitario Quiron-Dexeus (IOR), Barcelona, , Spain
University Hospital Vall d'Hebron, Barcelona, , Spain
Hospital Universitario Lucus Augusti, Lugo, , Spain
General University Hospital Gregorio Maranon, Madrid, , Spain
Hospital Puerta de Hierro, Madrid, , Spain
University Hospital Foundation Jimenez Diaz, Madrid, , Spain
University Hospital La Paz, Madrid, , Spain
Hospital Regional Universitario, Malaga, , Spain
University Hospital Virgen de Valme, Sevilla, , Spain
CHU Xeral, Vigo, , Spain