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Brief Title: Study Evaluating the Safety and Efficacy of PTX-022 (QTORIN Sirolimus) in the Treatment of Microcystic Lymphatic Malformations
Official Title: A Multicenter, Phase 2, Open-Label Study Evaluating The Safety And Efficacy of Sirolimus 3.9% Topical Gel (PTX-022) In The Treatment of Microcystic Lymphatic Malformations
Study ID: NCT05050149
Brief Summary: This study evaluates the safety and efficacy of PTX-022 (sirolimus) Topical Gel 3.9% w/w in the treatment of Microcystic Lymphatic Malformations. The participant will receive 3 months of PTX-022 treatment by the end of the study.
Detailed Description:
Minimum Age: 13 Years
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Arkansas Children's Hospital, Little Rock, Arkansas, United States
Stanford University, Palo Alto, California, United States
Minnesota Clinical Study Center, Fridley, Minnesota, United States
Vascular Birthmark Institute, New York, New York, United States
Cincinnati Children's Hospital, Cincinnati, Ohio, United States
Oregon Health and Science University, Portland, Oregon, United States
Children's Hospital of Pennsylvania (CHOP), Philadelphia, Pennsylvania, United States