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Brief Title: An Open Label Study of Itacitinib Administered Orally in Patients With Myelofibrosis
Official Title: An Open-Label, Multiple Simon 2-Stage Study of Itacitinib Administered Orally to Subjects With Primary Myelofibrosis (PMF), Post Polycythemia Vera Myelofibrosis (PPV-MF) or Post Essential Thrombocythemia Myelofibrosis (PET-MF)
Study ID: NCT01633372
Brief Summary: This is a study of itacitinib (INCB039110) in patients with myelofibrosis. This study will evaluate safety and efficacy parameters of itacitinib (INCB039110).
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Birmingham Hematology Oncology Associates, LLC, Birmingham, Alabama, United States
Mayo Clinic, Arizona, Scottsdale, Arizona, United States
UCLA Hematology & Oncology, Los Angeles, California, United States
Emory University, Atlanta, Georgia, United States
St Agnes Hospital, Baltimore, Maryland, United States
University of Michigan Cancer Center, Ann Arbor, Michigan, United States
Mount Sinai School of Medicine, New York, New York, United States
Oregon Health & Science University, Portland, Oregon, United States
University of Pennsylvania Health System, Philadelphia, Pennsylvania, United States
Western Pennsylvania Hospital, Pittsburgh, Pennsylvania, United States
South Carolina Oncology & Associates, Columbia, South Carolina, United States
Boston Baskin Cancer Foundation, Inc., Memphis, Tennessee, United States
Tennessee Oncology, Nashville, Tennessee, United States
MD Anderson Cancer Center, Houston, Texas, United States
St Vincent's Hospital, Darlinghurst, New South Wales, Australia
St. George Hospital, Kogarah, New South Wales, Australia
Box Hill Hospital, Box Hill, Victoria, Australia
Frankston Hospital, Frankston, Victoria, Australia
Cross Cancer Institute, Edmonton, Alberta, Canada
St. Paul's Hospital, Vancouver, British Columbia, Canada
Princess Margaret Hospital, Toronto, Ontario, Canada
St. Mary's Hospital, Montreal, Quebec, Canada
Name: Albert Assad, MD
Affiliation: Incyte Corporation
Role: STUDY_DIRECTOR