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Brief Title: Anti-BCMA CAR-NK Cell Therapy for the Relapsed or Refractory Multiple Myeloma
Official Title: Phase I Study to Evaluate the Safety and Effectiveness of Anti-BCMA CAR-NK Therapy in Relapsed or Refractory Multiple Myeloma
Study ID: NCT05008536
Brief Summary: The purpose of this study is to infuse BCMA CAR-NK cells(Umbilical \& Cord Blood (CB) Derived CAR-Engineered NK Cells) to the patients with relapsed and refractory multiple myeloma (MM), to assess the safety and feasibility of this strategy. The CAR enables the NK cells to recognize and kill the MM cells by targeting of BCMA, a protein expressed of the surface of the malignant plasma cells in MM patients.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Department of Hematology, Xinqiao Hospital, Chongqing, Chongqing, China
Name: xi zhang, PhD/MD
Affiliation: Department of Hematology, Xinqiao Hospital
Role: PRINCIPAL_INVESTIGATOR