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Spots Global Cancer Trial Database for A Multi-center Open-label Phase 2 Study of Ixazomib, Iberdomide and Dexamethasone in Elderly Patients With Multiple Myeloma at First Relapse."

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Trial Identification

Brief Title: A Multi-center Open-label Phase 2 Study of Ixazomib, Iberdomide and Dexamethasone in Elderly Patients With Multiple Myeloma at First Relapse."

Official Title: A Multi-center Open-label Phase 2 Study of Ixazomib, Iberdomide and Dexamethasone in Elderly Patients With Multiple Myeloma at First Relapse."

Study ID: NCT04998786

Study Description

Brief Summary: This is a phase II, multicenter, open-label study to evaluate the rate of patients achieving very good partial response (VGPR) or better to the oral combination Iberdomide Ixazomib Dexamethasone in elderly patients with multiple myeloma at first relapse . The patient population will consist of adult men and women more than 70 years, who meet eligibility criteria. Following the screening period, patients will be enrolled and treated then, they will receive therapy with Iberdomide, Ixazomib and Dexaméthasone during 6 cycles and Iberdomide and Ixazomib until progression.

Detailed Description:

Eligibility

Minimum Age: 70 Years

Eligible Ages: OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

CHR, Annecy, , France

CH de la cote basque, Bayonne, , France

CHRU Hopital Haut Lévêque, Bordeaux, , France

CHU de Brest, Brest, , France

CHU, Caen, , France

CHU, Clermont-Ferrand, , France

CHRU, Dijon, , France

CHD les Oudairies, La Roche-sur-Yon, , France

CHRU Lille, Lille, , France

CHU, Limoges, , France

CH Lyon Sud, Lyon, , France

CHRU, Nancy, , France

CHU, Nantes, , France

Hopital de l'archet, Nice, , France

CHU Henri Mondor, Paris, , France

Hopital St Antoine, Paris, , France

Hôpital Cochin, Paris, , France

University Hospital, Poitiers, , France

CHRU, Rennes, , France

ICANS, Strasbourg, , France

CHU, Toulouse, , France

CHRU Bretonneau, Tours, , France

Contact Details

Name: Cyrille Touzeau

Affiliation: Nantes University Hospital

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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