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Brief Title: Natural Killer Cell (CYNK-001) Infusions in Adults With Multiple Myeloma
Official Title: A Phase I Study of Human Placental Hematopoietic Stem Cell Derived Natural Killer Cells (CYNK 001) in Multiple Myeloma Patients Following Autologous Stem Cell Transplant in the Front-line Setting.
Study ID: NCT04309084
Brief Summary: This study will find the maximum tolerated dose (MTD) of CYNK-001 which contain NK cells derived from human placental CD34+ cells and culture-expanded. CYNK-001 cells will be given post Autologous Stem Cell Transplant (ASCT). The safety of this treatment will be evaluated, and researchers will want to learn if NK cells will help in treating Multiple Myeloma.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Colorado Blood Cancer Institute, Denver, Colorado, United States
Washington University, Saint Louis, Missouri, United States
Roswell Park Comprehensive Cancer Institute, Buffalo, New York, United States
Tennessee Oncology, Nashville, Tennessee, United States
Name: Adrian Kilcoyne, MD
Affiliation: Celularity Incorporated
Role: STUDY_DIRECTOR