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Brief Title: A Study to Evaluate Efficacy and Safety of Alnuctamab Compared to Standard of Care Regimens in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
Official Title: A Phase 3, Randomized, Multicenter, Open-label Study to Evaluate the Efficacy and Safety of Alnuctamab Compared to Standard of Care Regimens in Participants With Relapsed or Refractory Multiple Myeloma (RRMM) - ALUMMINATE RRMM
Study ID: NCT06232707
Brief Summary: The purpose of this study is to evaluate the efficacy and safety of alnuctamab compared to standard of care regimens in participants with relapsed or refractory multiple myeloma (RRMM).
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Local Institution - 0151, Birmingham, Alabama, United States
Local Institution - 0088, Los Angeles, California, United States
Local Institution - 0358, Stanford, California, United States
Local Institution - 0355, New Haven, Connecticut, United States
Local Institution - 0434, Washington, District of Columbia, United States
Local Institution - 0433, Wichita, Kansas, United States
Local Institution - 0439, Saint Matthews, Kentucky, United States
Local Institution - 0323, New Orleans, Louisiana, United States
Local Institution - 0324, Baltimore, Maryland, United States
Local Institution - 0441, Bethesda, Maryland, United States
Local Institution - 0435, Billings, Montana, United States
Local Institution - 0157, Hackensack, New Jersey, United States
Local Institution - 0359, Summit, New Jersey, United States
Local Institution - 0430, Lake Success, New York, United States
Local Institution - 0396, New York, New York, United States
Local Institution - 0306, Cincinnati, Ohio, United States
Local Institution - 0199, Cleveland, Ohio, United States
Local Institution - 0437, Pittsburgh, Pennsylvania, United States
Local Institution - 0352, Providence, Rhode Island, United States
Local Institution - 0420, Watertown, South Dakota, United States
Local Institution - 0168, Dallas, Texas, United States
Local Institution - 0405, Seattle, Washington, United States
Local Institution - 0222, Florencio Varela, Buenos Aires, Argentina
Local Institution - 0001, La Plata, Buenos Aires, Argentina
Local Institution - 0262, Pilar, Buenos Aires, Argentina
Local Institution - 0002, Buenos Aires, Ciudad Autónoma De Buenos Aires, Argentina
Local Institution - 0260, Liverpool, New South Wales, Australia
Local Institution - 0246, Macquarie University, New South Wales, Australia
Local Institution - 0022, Waratah, New South Wales, Australia
Local Institution - 0397, Brisbane, Queensland, Australia
Local Institution - 0021, Box Hill, Victoria, Australia
Local Institution - 0019, Clayton, Victoria, Australia
Local Institution - 0018, Melbourne, Victoria, Australia
Local Institution - 0003, Melbourne, Victoria, Australia
Local Institution - 0333, St. Polten, Niederösterreich, Austria
Local Institution - 0337, Innsbruck, Tirol, Austria
Local Institution - 0334, Salzburg, , Austria
Local Institution - 0332, Wien, , Austria
Local Institution - 0284, Brasschaat, Antwerpen, Belgium
Local Institution - 0280, Verviers, Liège, Belgium
Local Institution - 0279, Yvoir, Namur, Belgium
Local Institution - 0286, Leuven, Vlaams-Brabant, Belgium
Local Institution - 0274, Belo Horizonte, Minas Gerais, Brazil
Local Institution - 0351, Natal, Rio Grande Do Norte, Brazil
Local Institution - 0369, Sao Paulo, São Paulo, Brazil
Local Institution - 0291, Rio de Janeiro, , Brazil
Local Institution - 0211, São Paulo, , Brazil
Local Institution - 0417, Calgary, Alberta, Canada
Local Institution - 0423, Edmonton, Alberta, Canada
Local Institution - 0402, London, Ontario, Canada
Local Institution - 0395, Toronto, Ontario, Canada
Local Institution - 0031, Montreal, Quebec, Canada
Local Institution - 0098, Montréal, Quebec, Canada
Local Institution - 0027, Santiago, Metropolitana DE Santiago, Chile
Local Institution - 0030, Santiago, Región Metropolitana De Santiago, Chile
Local Institution - 0026, Santiago, Región Metropolitana De Santiago, Chile
Local Institution - 0029, Santiago, Región Metropolitana De Santiago, Chile
Local Institution - 0413, Beijing, Beijing, China
Local Institution - 0230, Beijing, Beijing, China
Local Institution - 0040, Beijing, Beijing, China
Local Institution - 0366, Changping, Beijing, China
Local Institution - 0057, Chongqing, Chongqing, China
Local Institution - 0066, Guangzhou, Guangdong, China
Local Institution - 0080, Guangzhou, Guangdong, China
Local Institution - 0226, Guangzhou, Guangdong, China
Local Institution - 0368, Shenzhen, Guangdong, China
Local Institution - 0365, Baoding, Hebei, China
Local Institution - 0082, Shijiazhuang, Hebei, China
Local Institution - 0041, Zhengzhou, Henan, China
Local Institution - 0075, Wuhan, Hubei, China
Local Institution - 0062, Changsha, Hunan, China
Local Institution - 0053, Changsha, Hunan, China
Local Institution - 0055, Nanjing, Jiangsu, China
Local Institution - 0067, Suzhou, Jiangsu, China
Local Institution - 0377, Xuzhou, Jiangsu, China
Local Institution - 0044, Shenyang, Liaoning, China
Local Institution - 0072, Xi'An, Shaanxi, China
Local Institution - 0077, Jinan, Shandong, China
Local Institution - 0083, Jinan, Shandong, China
Local Institution - 0273, Shanghai, Shanghai, China
Local Institution - 0421, Shanghai, Shanghai, China
Local Institution - 0245, Taiyuan, Shanxi, China
Local Institution - 0056, Tianjin, Tianjin, China
Local Institution - 0422, Tianjin, Tianjin, China
Local Institution - 0070, Hangzhou, Zhejiang, China
Local Institution - 0203, Hangzhou, Zhejiang, China
Local Institution - 0367, Qingdao, , China
Local Institution - 0013, Brno, Brno-město, Czechia
Local Institution - 0247, Olomouc, Olomoucký Kraj, Czechia
Local Institution - 0012, Praha 2, , Czechia
Local Institution - 0118, Toulouse, Haute-Garonne, France
Local Institution - 0225, Montpellier, Languedoc-Roussillon, France
Local Institution - 0224, Vandoeuvre lès Nancy, Lorraine, France
Local Institution - 0084, Lille, Nord, France
Local Institution - 0085, Nantes, Pays-de-la-Loire, France
Local Institution - 0192, Pierre-Bénite, Rhône, France
Local Institution - 0331, Heidelberg, Baden-Württemberg, Germany
Local Institution - 0330, Tübingen, Baden-Württemberg, Germany
Local Institution - 0335, Dresden, Sachsen, Germany
Local Institution - 0329, Leipzig, Sachsen, Germany
Local Institution - 0339, Hamburg, , Germany
Local Institution - 0004, Athens, Attikí, Greece
Local Institution - 0136, Chaidari, Attikí, Greece
Local Institution - 0103, Nyiregyhaza, Szabolcs-Szatmár-Bereg, Hungary
Local Institution - 0108, Szombathely, Vas, Hungary
Local Institution - 0104, Budapest, , Hungary
Local Institution - 0105, Budapest, , Hungary
Local Institution - 0370, Visakhapatnam, Andhra Pradesh, India
Local Institution - 0362, Gurugram, Haryana, India
Local Institution - 0403, Bangalore, Karnataka, India
Local Institution - 0399, Lucknow, Uttar Pradesh, India
Local Institution - 0398, Kolkata, West Bengal, India
Local Institution - 0281, Cork, , Ireland
Local Institution - 0371, Dublin, , Ireland
Local Institution - 0285, Dublin, , Ireland
Local Institution - 0269, Limerick, , Ireland
Local Institution - 0096, Meldola, Emilia-Romagna, Italy
Local Institution - 0294, Legnano, Milano, Italy
Local Institution - 0265, Milan, Milano, Italy
Local Institution - 0410, Palermo, Sicilia, Italy
Local Institution - 0409, Anjo, Aichi, Japan
Local Institution - 0387, Nagoya, Aichi, Japan
Local Institution - 0407, Kamogawa, Chiba, Japan
Local Institution - 0385, Kashiwa, Chiba, Japan
Local Institution - 0386, Isehara, Kanagawa, Japan
Local Institution - 0390, Osaka-sayama, Osaka, Japan
Local Institution - 0381, Shimotsuga, Tochigi, Japan
Local Institution - 0382, Koto, Tokyo, Japan
Local Institution - 0419, Aomori, , Japan
Local Institution - 0383, Chiba, , Japan
Local Institution - 0391, Kumamoto, , Japan
Local Institution - 0389, Kyoto, , Japan
Local Institution - 0388, Okayama, , Japan
Local Institution - 0384, Tokyo, , Japan
Local Institution - 0240, Seongnam, Kyǒnggi-do, Korea, Republic of
Local Institution - 0221, Busan, Pusan-Kwangyǒkshi, Korea, Republic of
Local Institution - 0036, Seoul, Seoul-teukbyeolsi [Seoul], Korea, Republic of
Local Institution - 0239, Seoul, Seoul-teukbyeolsi [Seoul], Korea, Republic of
Local Institution - 0034, Seoul, Seoul-teukbyeolsi [Seoul], Korea, Republic of
Local Institution - 0035, Seoul, Seoul-teukbyeolsi [Seoul], Korea, Republic of
Local Institution - 0137, Løenskog, Akershus, Norway
Local Institution - 0115, Bergen, Hordaland, Norway
Local Institution - 0193, Oslo, , Norway
Local Institution - 0242, Lisbon, Lisboa, Portugal
Local Institution - 0415, Lisbon, Lisboa, Portugal
Local Institution - 0255, Lisboa, , Portugal
Local Institution - 0169, Bucuresti, București, Romania
Local Institution - 0171, Brasov, , Romania
Local Institution - 0414, București, , Romania
Local Institution - 0011, Badalona, Barcelona [Barcelona], Spain
Local Institution - 0234, El Palmar, Murcia, Murcia, Región De, Spain
Local Institution - 0008, Pamplona, Navarra, Spain
Local Institution - 0202, Jerez de la Frontera, , Spain
Local Institution - 0006, Salamanca, , Spain
Local Institution - 0007, Santiago de Compostela, , Spain
Local Institution - 0009, València, , Spain
Local Institution - 0114, Borås, Västra Götalands Län [se-14], Sweden
Local Institution - 0111, Gothenburg, Västra Götalands Län [se-14], Sweden
Local Institution - 0336, Bern, Berne, Switzerland
Local Institution - 0411, st.Gallen, Sankt Gallen, Switzerland
Local Institution - 0338, Zürich, , Switzerland
Local Institution - 0325, Stanbul, İstanbul, Turkey
Local Institution - 0375, Ankara, , Turkey
Local Institution - 0188, İzmir, , Turkey
Local Institution - 0187, Kayseri, , Turkey
Local Institution - 0349, Southampton, Hampshire, United Kingdom
Local Institution - 0342, London, London, City Of, United Kingdom
Local Institution - 0350, Cardiff, , United Kingdom
Local Institution - 0344, Derby, , United Kingdom
Local Institution - 0343, Manchester, , United Kingdom
Name: Bristol-Myers Squibb
Affiliation: Bristol-Myers Squibb
Role: STUDY_DIRECTOR