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Brief Title: A Study of CC-5013 Plus Dexamethasone Versus Dexamethasone Alone in Previously Treated Subjects With Multiple Myeloma
Official Title: The Official Title is A Multi-center, Randomized, Parallel-group, Double-blind, Placebo Controlled Study of CC-5013 Plus Dexamethasone Versus Dexamethasone Alone in Previously Treated Subjects With Multiple Myeloma.
Study ID: NCT00424047
Brief Summary: To compare the efficacy of oral CC-5013 in combination with oral pulse high-dose dexamethasone to that of placebo and oral high-dose pulse dexamethasone as treatment for subjects with relapsed or refractory multiple myeloma."
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
Peter MacCallum Cancer Centre Divsion of Haematology/Medical Oncology, East Melbourne, Victoria, Australia
The Alfred Hospital, Prahran, Victoria, Australia
Border Medical Oncology, Wodonga, Victoria, Australia
Box Hill Hospital, Box Hill, , Australia
Frankston Hospital Oncology Research, Frankston, , Australia
Royal Brisbane Hospital, Herston, , Australia
The Royal Melbourne Hospital, Parkville, , Australia
Mater Public Hospital, South Brisbane, , Australia
University Hospital of Salzburg St Johanns Spital, Salzburg, , Austria
Wilhelminenspital, Vienna, , Austria
CHU Saint-Luc, Brussel, , Belgium
UZ Gasthuisberg, Leuven, , Belgium
Centre Hospitalier Lyon Sud, Chemin Grand Revoyet, , France
Hopital Claude Huriez, Lille, , France
Centre Hospitalier Hotel-Dieu, Nantes, , France
Hopital Saint-Loius, Paris, , France
Chu de Bordeaux Groupe Hospitalier Sud, Pessac, , France
CHU Purpan, Toulouse cedex 9, , France
CHU Nancy - Hopital Brabois, Vandoeuvre, , France
Universitaetsklinikum Charite, Berlin, , Germany
Universitatsklinik ChariteMedizinische Fakultaet der HumboldtUniversitaet zu Berlin, Berlin, , Germany
Universitaetsklinikum Dusseldorf Klinik fuer Haematologie, Dusseldorf, , Germany
Universitaetsklinkum Erlangen, Erlangen, , Germany
Klininkum der Johann-Wolfgang-Goethe-Universtat, Frankfurt am Main, , Germany
Universitaetsklinikum Heidelberg Medizinische Klinik und Poliklinik V, Heidelberg, , Germany
Universitatsklinik Muenster Medizinische Klinik A, Muenster, , Germany
Klinikum der Univeristact Muenchen, Munchen, , Germany
Universitaetsklinikum Tuebingen, Tubingen, , Germany
"Alexandras" General Hospital of Athens, Athens, , Greece
University Hospital GalwayHaematology Department, Galway, Co. Galway, Ireland
Belfast City HospitalHaematology Department, Belfast, , Ireland
Hope Directorate Haematology Oncology Service St. James Hospital, Dublin 8, , Ireland
MidWestern Regional Hospital, Limerick, , Ireland
Rambam Medical Center, Haifa, , Israel
Hadassah University Hospital, Jerusalem, , Israel
Tel Aviv Sourasky Medical Center Department of Hematology, Tel Aviv, , Israel
The Chaim Sheba Medical Center, Tel Hashomer, , Israel
Policlinico Sant'Orsola-Malpighi, Bologna, , Italy
Azienda Ospedaliera San Martino, Genova, , Italy
Ospedale Niguarda Ca Granda, Milano, , Italy
Policlinico San Matteo, Pavia, , Italy
Univerita La Sapien, Roma, , Italy
Azienda Sanitaria Ospedaliera Molinette S. Giovanni Battista, Torio, , Italy
Policlinico Universitario a Gesttione diretta di Udine, Udine, , Italy
Institute of Internal Diseases University of Medicine, Gdansk, , Poland
University School of Medicine, Lublin, , Poland
Institute of Haematology and Blood Transfusion, Warsaw, , Poland
Hospital Clinic, Barcelona, , Spain
Hospital Universitario de la Princessa, Madrid, , Spain
Hospital Doce de Octubre, Madrid, , Spain
Clinica Universitaria de Navarra, Pamplona, , Spain
Hospital Universitario de Salamanca, Salamanca, , Spain
Hospital Universtario Marques de Valdecilla, Santander, , Spain
Sahlgrenska University Hospital Department of Hematology and Coagulation, Goteborg, , Sweden
Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, , Switzerland
Kantonsspital St. Gallen, St. Gallen, , Switzerland
Universitätsspital Zürich, Zürich, , Switzerland
Cherkassy Regional Oncology Center, Cherkassy, , Ukraine
Dnepropetrovsk City Clinical Hospital #4, Dnepropetrovsk, , Ukraine
Kiev Bone Marrow Transplantation Center Bone Marrow Department, Kiev, , Ukraine
Institute of Hematology and Transfusiology of the UAMS Department of blood diseases, Kiev, , Ukraine
Institute of Blood Pathology and Transfusion Medicine of the UAMS, Lviv, , Ukraine
Institute of Blood Pathology and Transfusion Medicine of the UAMS Hematology Department, Lvov, , Ukraine
Odess Regional Clinical Hospital, Odessa, , Ukraine
Zhitomir Regional Clinical Hospital, Zhitomir, , Ukraine
University College Hospital Trust, London, Bloomsbury, United Kingdom
Bristol Haematology and Oncology Centre, Bristol, , United Kingdom
Haematology Dept, 4th Floor Thomas Guy House, London, , United Kingdom
Name: Robert Knight, MD
Affiliation: Celgene Corporation
Role: STUDY_DIRECTOR