Spots Global Cancer Trial Database for Once-weekly Versus Twice-weekly Carfilzomib in Combination With Dexamethasone in Adults With Relapsed and Refractory Multiple Myeloma
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Trial Identification
Brief Title: Once-weekly Versus Twice-weekly Carfilzomib in Combination With Dexamethasone in Adults With Relapsed and Refractory Multiple Myeloma
Official Title: A Randomized, Open-label, Phase 3 Study in Subjects With Relapsed and Refractory Multiple Myeloma Receiving Carfilzomib in Combination With Dexamethasone, Comparing Once-weekly Versus Twice-weekly Carfilzomib Dosing
Study ID: NCT02412878
Conditions
Study Description
Brief Summary: The purpose of the study is to compare the progression-free survival (PFS) of once-weekly carfilzomib dosing in combination with dexamethasone to twice-weekly carfilzomib dosing in combination with dexamethasone in adults with relapsed and refractory multiple myeloma, previously treated with bortezomib and an immunomodulatory agent (IMiD).
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Research Site, Scottsdale, Arizona, United States
Mayo Clinic, Scottsdale, Arizona, United States
Research Site, Bethesda, Maryland, United States
Center for Cancer and Blood Disorders, Bethesda, Maryland, United States
Research Site, Rockville, Maryland, United States
Maryland Oncology Hematology, P.A, Rockville, Maryland, United States
Research Site, Hackensack, New Jersey, United States
John Theurer Cancer Center at Hackensack University Medical Center, Hackensack, New Jersey, United States
Research Site, New York, New York, United States
Research Site, Pittsburgh, Pennsylvania, United States
Research Site, Tyler, Texas, United States
Blood and Cancer Center of East Texas, Tyler, Texas, United States
Research Site, Darlinghurst, New South Wales, Australia
Research Site, Tweed Heads, New South Wales, Australia
Research Site, Waratah, New South Wales, Australia
Research Site, Box Hill, Victoria, Australia
Research Site, Antwerpen, , Belgium
Research Site, Brugge, , Belgium
Research Site, Brussel, , Belgium
Research Site, Bruxelles, , Belgium
Research Site, Ghent, , Belgium
Research Site, Leuven, , Belgium
Research Site, Calgary, Alberta, Canada
Research Site, Kelowna, British Columbia, Canada
Research Site, Vancouver, British Columbia, Canada
Research Site, St. Johns, Newfoundland and Labrador, Canada
Research Site, Halifax, Nova Scotia, Canada
Research Site, Ottawa, Ontario, Canada
Research Site, Toronto, Ontario, Canada
Research Site, Montreal, Quebec, Canada
Research Site, Quebec, , Canada
Research Site, Brno, , Czechia
Research Site, Hradec Kralove, , Czechia
Research Site, Olomouc, , Czechia
Research Site, Ostrava-Poruba, , Czechia
Research Site, Praha 10, , Czechia
Research Site, Praha, , Czechia
Research Site, Aalborg, , Denmark
Research Site, Copenhagen, , Denmark
Research Site, Odense C, , Denmark
Research Site, Vejle, , Denmark
Research Site, Helsinki, , Finland
Research Site, Tampere, , Finland
Research Site, Turku, , Finland
Research Site, Bayonne, , France
Research Site, Brest, , France
Research Site, Dijon, , France
Research Site, Nantes Cedex 1, , France
Research Site, Nimes cedex 09, , France
Research Site, Paris, , France
Research Site, Pierre-Benite cedex, , France
Research Site, Rennes, , France
Research Site, Tours Cedex 1, , France
Research Site, Köln, , Germany
Research Site, Leipzig, , Germany
Research Site, München, , Germany
Research Site, Rostock, , Germany
Research Site, Tubingen, , Germany
Research Site, Athens, , Greece
Research Site, Athens, , Greece
Research Site, Patra, , Greece
Research Site, Budapest, , Hungary
Research Site, Debrecen, , Hungary
Research Site, Gyula, , Hungary
Research Site, Kaposvar, , Hungary
Research Site, Ancona, , Italy
Research Site, Bologna, , Italy
Research Site, Brescia, , Italy
Research Site, Cagliari, , Italy
Research Site, Catania, , Italy
Research Site, Firenze, , Italy
Research Site, Genova, , Italy
Research Site, Napoli, , Italy
Research Site, Pavia, , Italy
Research Site, Piacenza, , Italy
Research Site, Pisa, , Italy
Research Site, Roma, , Italy
Research Site, Roma, , Italy
Research Site, Torino, , Italy
Research Site, Toyohashi-shi, Aichi, Japan
Research Site, Fukuoka-shi, Fukuoka, Japan
Research Site, Ogaki-shi, Gifu, Japan
Research Site, Maebashi-shi, Gunma, Japan
Research Site, Shibukawa-shi, Gunma, Japan
Research Site, Sapporo-shi, Hokkaido, Japan
Research Site, Isehara-shi, Kanagawa, Japan
Research Site, Kyoto-shi, Kyoto, Japan
Research Site, Sendai-shi, Miyagi, Japan
Research Site, Okayama-shi, Okayama, Japan
Research Site, Suita-shi, Osaka, Japan
Research Site, Kawagoe-shi, Saitama, Japan
Research Site, Utsunomiya-shi, Tochigi, Japan
Research Site, Chuo-ku, Tokyo, Japan
Research Site, Koto-ku, Tokyo, Japan
Research Site, Shibuya-ku, Tokyo, Japan
Research Site, Tachikawa-shi, Tokyo, Japan
Research Site, Fukuoka-shi, , Japan
Research Site, Nagoya-shi, , Japan
Research Site, Niigata-shi, , Japan
Research Site, Tokushima-shi, , Japan
Research Site, Christchurch, , New Zealand
Research Site, Otahuhu, Auckland, , New Zealand
Research Site, Oslo, , Norway
Research Site, Trondheim, , Norway
Research Site, Brzozow, , Poland
Research Site, Chorzow, , Poland
Research Site, Katowice, , Poland
Research Site, Krakow, , Poland
Research Site, Lodz, , Poland
Research Site, Olsztyn, , Poland
Research Site, Poznan, , Poland
Research Site, Torun, , Poland
Research Site, Warszawa, , Poland
Research Site, Wroclaw, , Poland
Research Site, Brazov, , Romania
Research Site, Bucharest, , Romania
Research Site, Sevilla, Andalucía, Spain
Research Site, Zaragoza, Aragón, Spain
Research Site, Palma de Mallorca, Baleares, Spain
Research Site, Salamanca, Castilla León, Spain
Research Site, Badalona, Cataluña, Spain
Research Site, Barcelona, Cataluña, Spain
Research Site, Girona, Cataluña, Spain
Research Site, Pamplona, Navarra, Spain
Research Site, Madrid, , Spain
Research Site, Madrid, , Spain
Research Site, Madrid, , Spain
Research Site, Goteborg, , Sweden
Research Site, Helsingborg, , Sweden
Research Site, Lund, , Sweden
Research Site, Stockholm, , Sweden
Research Site, Stockholm, , Sweden
Research Site, Uddevalla, , Sweden
Research Site, Bournemouth, , United Kingdom
Research Site, London, , United Kingdom
Research Site, London, , United Kingdom
Research Site, Manchester, , United Kingdom
Research Site, Nottingham, , United Kingdom
Research Site, Sheffield, , United Kingdom
Research Site, Wolverhampton, , United Kingdom
Contact Details
Name: MD
Affiliation: Amgen
Role: STUDY_DIRECTOR
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