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Brief Title: Phase III Study of Lenalidomide and Dexamethasone With or Without Elotuzumab to Treat Newly Diagnosed, Previously Untreated Multiple Myeloma
Official Title: A Phase 3, Randomized, Open Label Trial of Lenalidomide/Dexamethasone With or Without Elotuzumab in Subjects With Previously Untreated Multiple Myeloma
Study ID: NCT01335399
Brief Summary: The purpose of the study is to determine whether the addition of Elotuzumab to Lenalidomide/low-dose Dexamethasone will increase the progression free survival (PFS)
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Local Institution - 1628, Birmingham, Alabama, United States
Local Institution - 7619, Mobile, Alabama, United States
Local Institution - 7618, Mobile, Alabama, United States
Local Institution - 7617, Chandler, Arizona, United States
Local Institution - 1644, Tucson, Arizona, United States
Local Institution - 1618, Bakersfield, California, United States
Local Institution - 1602, Berkeley, California, United States
Local Institution - 1636, Corona, California, United States
Local Institution - 1668, Corona, California, United States
Local Institution - 1616, Greenbrae, California, United States
Local Institution - 7609, Long Beach, California, United States
Local Institution - 1660, Los Angeles, California, United States
Local Institution - 1673, Orange, California, United States
Local Institution - 1613, San Diego, California, United States
Local Institution - 1621, New Haven, Connecticut, United States
Local Institution - 1612, Washington, District of Columbia, United States
Local Institution - 1682, Boca Raton, Florida, United States
Local Institution - 1617, Brooksville, Florida, United States
Local Institution - 1648, Fort Myers, Florida, United States
Local Institution - 7613, Hollywood, Florida, United States
Local Institution - 1623, Jacksonville, Florida, United States
Local Institution - 1625, New Port Richey, Florida, United States
Local Institution - 1649, Saint Petersburg, Florida, United States
Local Institution - 1611, West Palm Beach, Florida, United States
Local Institution - 1630, Atlanta, Georgia, United States
Local Institution - 1684, Honolulu, Hawaii, United States
Local Institution - 1607, Chicago, Illinois, United States
Local Institution - 1635, Chicago, Illinois, United States
Local Institution - 1632, Maywood, Illinois, United States
Local Institution - 7606, Peoria, Illinois, United States
Local Institution - 7610, Skokie, Illinois, United States
Local Institution - 1603, Urbana, Illinois, United States
Local Institution - 7616, Bloomington, Indiana, United States
Local Institution - 7620, Indianapolis, Indiana, United States
Local Institution - 1669, Indianapolis, Indiana, United States
Local Institution - 1656, Mishawaka, Indiana, United States
Local Institution - 1633, Iowa City, Iowa, United States
Local Institution - 1674, Lexington, Kentucky, United States
Local Institution - 1683, Louisville, Kentucky, United States
Local Institution - 1646, Lafayette, Louisiana, United States
Local Institution - 7614, Marrero, Louisiana, United States
Local Institution - 1626, New Orleans, Louisiana, United States
Local Institution - 1652, Shreveport, Louisiana, United States
Local Institution - 1676, Baltimore, Maryland, United States
Local Institution - 1650, Baltimore, Maryland, United States
Local Institution - 1619, Boston, Massachusetts, United States
Local Institution - 1699, Boston, Massachusetts, United States
Local Institution - 1604, Detroit, Michigan, United States
Local Institution - 1667, Jefferson City, Missouri, United States
Local Institution - 1645, Saint Louis, Missouri, United States
Local Institution - 1651, Springfield, Missouri, United States
Local Institution - 1637, Omaha, Nebraska, United States
Local Institution - 7621, Mineola, New York, United States
Local Institution - 1615, New York, New York, United States
Local Institution - 1671, Stony Brook, New York, United States
Local Institution - 7604, Goldsboro, North Carolina, United States
Local Institution - 1610, Winston-Salem, North Carolina, United States
Local Institution - 1608, Cleveland, Ohio, United States
Local Institution - 1693, Cleveland, Ohio, United States
Local Institution - 1638, Columbus, Ohio, United States
Local Institution - 1664, Columbus, Ohio, United States
Local Institution - 1690, Middletown, Ohio, United States
Local Institution - 1655, Tulsa, Oklahoma, United States
Local Institution - 7611, Langhorne, Pennsylvania, United States
Local Institution - 1647, Pittsburgh, Pennsylvania, United States
Local Institution - 1679, Pittsburgh, Pennsylvania, United States
Local Institution - 1677, Sayre, Pennsylvania, United States
Local Institution - 1629, Charleston, South Carolina, United States
Local Institution - 7615, Charleston, South Carolina, United States
Local Institution - 1624, Greenville, South Carolina, United States
Local Institution - 7607, Sioux Falls, South Dakota, United States
Local Institution - 1600, Knoxville, Tennessee, United States
Local Institution - 7628, Memphis, Tennessee, United States
Local Institution - 1627, Nashville, Tennessee, United States
Local Institution - 1670, Nashville, Tennessee, United States
Local Institution - 1634, Corpus Christi, Texas, United States
Local Institution - 7612, Dallas, Texas, United States
Local Institution - 1643, Houston, Texas, United States
Local Institution - 1686, Houston, Texas, United States
Local Institution - 1642, Houston, Texas, United States
Local Institution - 7623, Ogden, Utah, United States
Local Institution - 1657, Fredericksburg, Virginia, United States
Local Institution - 1640, Seattle, Washington, United States
Local Institution - 1631, Seattle, Washington, United States
Local Institution - 1601, Huntington, West Virginia, United States
Gundersen Clinic, Ltd, La Crosse, Wisconsin, United States
Local Institution - 1663, Madison, Wisconsin, United States
Local Institution - 1609, Madison, Wisconsin, United States
Local Institution - 3600, Garran, Australian Capital Territory, Australia
Local Institution - 3607, Waratah, New South Wales, Australia
Local Institution - 3610, Westmead, New South Wales, Australia
Local Institution - 3609, Herston, Queensland, Australia
Local Institution - 3608, Milton, Queensland, Australia
Local Institution - 3612, Adelaide, South Australia, Australia
Local Institution - 3606, Woodville South, South Australia, Australia
Local Institution - 3601, Fitzroy, Victoria, Australia
Local Institution - 3602, Frankston, Victoria, Australia
Local Institution - 3603, Heidelberg Melbourne, Victoria, Australia
Local Institution - 3604, Wodonga, Victoria, Australia
Local Institution - 3605, Murdoch, , Australia
Local Institution - 3611, Nedlands, , Australia
Local Institution - 4052, Fadingerstraße 1, , Austria
Local Institution - 4051, Innsbruck, , Austria
Local Institution - 4054, Rankweil, , Austria
Local Institution - 4053, Wels, , Austria
Local Institution - 4160, Brussels, , Belgium
Local Institution - 4156, Brussels, , Belgium
Local Institution - 4157, Brussles, , Belgium
Local Institution - 4154, Charleroi, , Belgium
Local Institution - 4159, Haine St Paul, , Belgium
Local Institution - 4158, Leuven, , Belgium
Local Institution - 4150, Liege, , Belgium
Local Institution - 4153, Roeselare, , Belgium
Local Institution - 4151, Yvoir, , Belgium
Local Institution - 2601, Calgary, Alberta, Canada
Local Institution - 2600, Edmonton, Alberta, Canada
Local Institution - 2602, Winnipeg, Manitoba, Canada
Local Institution - 2611, Saint John, New Brunswick, Canada
Local Institution - 2610, Halifax, Nova Scotia, Canada
Local Institution - 2606, London, Ontario, Canada
Local Institution - 2612, Toronto, Ontario, Canada
Local Institution - 2603, Greenfield Park, Quebec, Canada
Local Institution - 2605, Montreal, Quebec, Canada
Local Institution - 2607, Montreal, Quebec, Canada
Local Institution - 4252, Hradec Kralove, , Czechia
Local Institution - 4250, Praha 10, , Czechia
Local Institution - 4251, Praha 2, , Czechia
Local Institution - 4565, Aschaffenburg, , Germany
Local Institution - 4550, Berlin, , Germany
Local Institution - 4555, Chemnitz, , Germany
Local Institution - 4562, Dresden, , Germany
Local Institution - 4552, Hamm, , Germany
Local Institution - 4553, Heidelberg, , Germany
Local Institution - 4560, Jena, , Germany
Local Institution - 4563, Koln, , Germany
Local Institution - 4554, Mainz, , Germany
Local Institution - 4561, Munchen, , Germany
Local Institution - 4558, Munster, , Germany
Local Institution - 4551, Offenbach, , Germany
Local Institution - 4556, Stuttgart, , Germany
Local Institution - 4564, Tuebingen, , Germany
Local Institution - 4559, Ulm, , Germany
Local Institution - 4653, Athens, , Greece
Local Institution - 4651, Athens, , Greece
Local Institution - 4650, Ioannina, , Greece
Local Institution - 4652, Larissa, , Greece
Local Institution - 4654, Patras, , Greece
Local Institution - 4751, Budapest, , Hungary
Local Institution - 4754, Budapest, , Hungary
Local Institution - 4750, Debrecen, , Hungary
Local Institution - 4753, Gyor, , Hungary
Local Institution - 4752, Szeged, , Hungary
Local Institution - 4852, Dublin, , Ireland
Local Institution - 4850, Dublin, , Ireland
Local Institution - 4851, Galway, , Ireland
Local Institution - 4950, Afula, , Israel
Local Institution - 4956, Ashkelon, , Israel
Local Institution - 4960, Haifa, , Israel
Local Institution - 4958, Jerusalem, , Israel
Local Institution - 4951, Jerusalem, , Israel
Local Institution - 4959, Kfar Saba, , Israel
Local Institution - 4954, Nahariya, , Israel
Local Institution - 4952, Petah Tikva, , Israel
Local Institution - 4957, Tel Aviv, , Israel
Local Institution - 4955, Zerifin, , Israel
Local Institution - 5067, Ancona, , Italy
Local Institution - 5065, Bari, , Italy
Local Institution - 5053, Bergamo, , Italy
Local Institution - 5070, Bologna, , Italy
Local Institution - 5066, Firenze, , Italy
Local Institution - 5050, Genova, , Italy
Local Institution - 5057, Meldola, , Italy
Local Institution - 5075, Milano, , Italy
Local Institution - 5069, Milan, , Italy
Local Institution - 5052, Monza, , Italy
Local Institution - 5062, Napoli, , Italy
Local Institution - 5068, Napoli, , Italy
Local Institution - 5055, Palermo, , Italy
Local Institution - 5063, Ravenna, , Italy
Local Institution - 5073, Reggio Nell Emilia (RE), , Italy
Local Institution - 5064, Rimini, , Italy
Local Institution - 5058, Roma, , Italy
Local Institution - 5054, Roma, , Italy
Local Institution - 5056, Rome, , Italy
Local Institution - 5072, Terni, , Italy
Local Institution - 5051, Torino, , Italy
Local Institution - 5250, Bialystok, , Poland
Local Institution - 5252, Chorzow, , Poland
Local Institution - 5254, Gdansk, , Poland
Local Institution - 7626, Krakow, , Poland
Local Institution - 5258, Lodz, , Poland
Local Institution - 5257, Lublin, , Poland
Local Institution - 5259, Poznan, , Poland
Local Institution - 5255, Szczecin, , Poland
Local Institution - 5256, Warszawa, , Poland
Local Institution - 5253, Warszawa, , Poland
Local Institution - 5260, Warszawa, , Poland
Local Institution - 5251, Wroclaw, , Poland
Local Institution - 7600, Ponce, , Puerto Rico
Local Institution - 7602, San Juan, , Puerto Rico
Local Institution - 5356, Brasov, , Romania
Local Institution - 5350, Bucaresti, , Romania
Local Institution - 5355, Bucuresti, , Romania
Local Institution - 5353, Bucuresti, , Romania
Local Institution - 5352, Bucuresti, , Romania
Local Institution - 5351, Lasi, , Romania
Local Institution - 5453, Samara, , Russian Federation
Local Institution - 5450, St. Petersburg, , Russian Federation
Local Institution - 5452, St. Petersburg, , Russian Federation
Local Institution - 5552, Badalona-barcelona, , Spain
Local Institution - 5559, Barcelona, , Spain
Local Institution - 5555, Barcelona, , Spain
Local Institution - 5561, La Laguna- Tenerife, , Spain
Local Institution - 5553, Madrid, , Spain
Local Institution - 5551, Madrid, , Spain
Local Institution - 5560, Madrid, , Spain
Local Institution - 5554, Madrid, , Spain
Local Institution - 5558, Pamplona, , Spain
Local Institution - 5550, Salamanca, , Spain
Local Institution - 5557, San Sebastian, , Spain
Local Institution - 5556, Toledo, , Spain
Local Institution - 5751, Bern, , Switzerland
Local Institution - 5750, St Gallen, , Switzerland
Local Institution - 5753, Zurich, , Switzerland
Local Institution - 5752, Zurich, , Switzerland
Local Institution - 5853, Izmir, Bornova, Turkey
Local Institution - 5851, Ankara, Dikimevi, Turkey
Local Institution - 5854, Izmir, Inciralti, Turkey
Local Institution - 5856, Gaziantep, , Turkey
Local Institution - 5951, Belfast, Antrim, United Kingdom
Local Institution - 5953, London, Greater London, United Kingdom
Local Institution - 5950, London, , United Kingdom
Local Institution - 5954, London, , United Kingdom
Local Institution - 5952, London, , United Kingdom
Local Institution - 5955, London, , United Kingdom
Name: Bristol-Myers Squibb
Affiliation: Bristol-Myers Squibb
Role: STUDY_DIRECTOR