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Spots Global Cancer Trial Database for Phase 2 Study of Carfilzomib in Relapsed Multiple Myeloma

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Trial Identification

Brief Title: Phase 2 Study of Carfilzomib in Relapsed Multiple Myeloma

Official Title: An Open-label, Single-arm, Phase 2 Study of Carfilzomib in Patients With Relapsed or Refractory Multiple Myeloma

Study ID: NCT00530816

Interventions

carfilzomib

Study Description

Brief Summary: To evaluate the best overall response rate, safety and tolerability of carfilzomib in patients with relapsed or refractory multiple myeloma.

Detailed Description: Two groups of patients with multiple myeloma were initially studied: bortezomib-naïve and bortezomib-treated. Following Amendment 2, only bortezomib-naïve patients were enrolled. Study results were reported in 2 parts, depending on whether a patient received prior bortezomib.

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Mayo Clinic Scottsdale, Scottsdale, Arizona, United States

Tower Cancer Research Foundation, Beverly Hills, California, United States

Therapeutic Research Institute of Orange County, Laguna Hills, California, United States

Rocky Mountain Blood and Marrow Transplant Program, Denver, Colorado, United States

Oncology & Hematology Assoc. of W. Broward, Tamarac, Florida, United States

H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, United States

Emory University Winship Cancer Institute, Atlanta, Georgia, United States

Northwestern University, Chicago, Illinois, United States

Orchard Research, Skokie, Illinois, United States

University of Kentucky College of Medicine, Lexington, Kentucky, United States

Montgomery Cancer Center, Mount Sterling, Kentucky, United States

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States

Mayo Clinic Rochester, Rochester, Minnesota, United States

Hattiesburg Clinic, Hattiesburg, Mississippi, United States

Jackson Oncology Associates, Jackson, Mississippi, United States

Washington University School of Medicine, Saint Louis, Missouri, United States

Hackensack University Medical Center, Hackensack, New Jersey, United States

St. Vincent's Comprehensive Cancer Center, New York, New York, United States

Summa Health System, Akron, Ohio, United States

Gabrail Cancer Center, Canton, Ohio, United States

Cleveland Clinic, Cleveland, Ohio, United States

Dayton Clinical Oncology Program, Dayton, Ohio, United States

Signal Point Clinical Research Center, LLC, Middletown, Ohio, United States

Harrington Cancer Center, Amarillo, Texas, United States

Texas Oncology Cancer Center, Austin, Texas, United States

MD Anderson Cancer Center, Houston, Texas, United States

University of Calgary, Calgary, Alberta, Canada

University of Alberta Cross Cancer Institute, Edmonton, Alberta, Canada

University of Toronto Princess Margaret Hospital, Toronto, Ontario, Canada

Royal Victoria Hospital, Montreal, Quebec, Canada

Contact Details

Name: MD

Affiliation: Amgen

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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