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Spots Global Cancer Trial Database for PS-341 (VELCADE™) Versus High-Dose Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma

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Trial Identification

Brief Title: PS-341 (VELCADE™) Versus High-Dose Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma

Official Title: An International, Multi-Center, Randomized, Open-Label Study of PS-341 (VELCADE™) Versus High-Dose Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma

Study ID: NCT00048230

Interventions

bortezomib

Study Description

Brief Summary: This study will compare the efficacy of PS-341 versus high dose dexamethasone.

Detailed Description:

Eligibility

Minimum Age:

Eligible Ages: CHILD, ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Alta Bates Comprehensive Cancer Center, Berkeley, California, United States

City of Hope, Duarte, California, United States

Scripps Clinic, La Jolla, California, United States

Loma Linda University Medical Center, Loma Linda, California, United States

Kaiser Permanente Oncology Clinical Trials, Vallejo, California, United States

Lombardi Cancer Center, Georgetown University Medical Center, Washington, District of Columbia, United States

Med Star Institute, Washington Cancer Center, Washington, District of Columbia, United States

Hematology/Oncology Associates, PA, Jacksonville, Florida, United States

University of Miami, Miami, Florida, United States

H. Lee Moffitt Cancer Center, University of S. Florida, Tampa, Florida, United States

Emory University, Atlanta, Georgia, United States

Northwestern University Medical School, Chicago, Illinois, United States

Loyola University Medical Center: Cardinal Bernardin Cancer Center, Maywood,, Illinois, United States

LSU HC, Shreveport, Louisiana, United States

Tufts New England Medical Center, Boston, Massachusetts, United States

Dana-Farber Cancer Center, Boston, Massachusetts, United States

Beth Israel Deaconess Medical Center, Kirstein Room 135, Boston, Massachusetts, United States

Department of Internal Medicine, Univ. of Michigan Comp. Cancer Center, Ann Arbor, Michigan, United States

VA Medical Center, Sections of Hematology/Oncology, Minneapolis, Minnesota, United States

Mayo Clinic, Rochester, Minnesota, United States

Washington University School of Medicine, St. Louis, Missouri, United States

Hackensack University Medical Center, David Jurist Research Building, Hackensack, New Jersey, United States

Roswell Park Cancer Institute, Buffalo, New York, United States

Long Island Jewish Medical Center, Division of Hematology/Oncology, New Hyde Park, New York, United States

St. Vincent's Comprehensive Cancer Center, Research Department, New York, New York, United States

NY Presbyterian Hospital, New York, New York, United States

Rochester General Hospital, Lipson Cancer Blood Center, Rochester, New York, United States

University of Rochester Medical Center, James P. Wilmot Cancer Center, Rochester, New York, United States

Carolinas Hematology-Oncology Associates, Charlotte, North Carolina, United States

Cleveland Clinic Foundation, Cleveland, Ohio, United States

University of Pennsylvania Cancer Center, Philadelphia, Pennsylvania, United States

Western Pennsylvania Hospital, Dept. of Human Oncology, Pittsburgh, Pennsylvania, United States

Trident Palmetto Hematology/Oncology, Charleston, South Carolina, United States

Division of Hematology/Stem Cell Transplant, Nashville, Tennessee, United States

Texas Oncology at Medical City Dallas Hospital, Dallas, Texas, United States

Baylor Institute for Immunology Research, Dallas, Texas, United States

MD Anderson Cancer Center, Houston, Texas, United States

Fred Hutchinson Cancer Center, Seattle, Washington, United States

Medical College of Wisconsin, Milwaukee, Wisconsin, United States

Wilhelminenspital Wien, Abt. Fur Med. und Medizinische Onkologie, Wien, , Austria

ACZA, Campus Stuivenberg, Antwerpen, , Belgium

CHU Erasme / ULB University, Hematology 7th Floor, Brussels, , Belgium

Institut Jules Bordet, Unite Sterile, Bruxelles, , Belgium

C.H. Notre Dame-Reine Fabiola, Charleroi, , Belgium

UZ Gasthuisberg, Department of Hematology, Leuven, , Belgium

AZ St. Jan, Dept. of Haematology, Rugge, , Belgium

Cliniques Universitaires U.C.L de Mont Godinne, Hopital de Jour, Yvoir, , Belgium

Cross Cancer Institute, Edmonton, Alberta, Canada

London Health Sciences Center, London, Ontario, Canada

Toronto General Research Institute, Princess Margaret Hospital, Toronto, Ontario, Canada

Royal Victoria Hospital, Montreal, Quebec, Canada

Hospital Claude Huriez, Service des Maladies du Sang, Lile, Cedex, France

Nantes Hotel Dieu Hospital, Nantes, Cedex, France

Hopital Purpan, Pavillon Dieulafoy, Service d'Hematologie Clinique, Toulouse, Cedex, France

Institut Gustave-Roussy, Service d'Hematologie, Villejuif, Cedex, France

Hopital Antoine Beclere, Hopital de Jour de Medecine Interne, Clamart, , France

Hopital Hotel Dieu, Service d'hematologie et oncologie medicale, Paris, , France

Hopital Saint-Louis, Direction Financiere, Paris, , France

Hopital Cochin, Service de Hematologie, Paris, , France

Centre Hospitalier Lyon Sud, Pierre Benite Cedex, , France

Hopital de Brabois, Service Hematologie et Medecine Interne, Vandoeuvre, , France

Universitatsklinikum Charite, Abt. Fuer Haematologie/Onkologie, Berlin, , Germany

Medizinische Klinik und Poliklinik 1, Bonn, , Germany

Universitatsklinikum Carl Gustav Carus, Dresden, , Germany

University of Erlangen-Nurenberg, Division of Hematology/Oncology, Erlangen, , Germany

Freiburg University Medical Center, Dept. of Hemayology/Oncology, Freiburg, , Germany

Medical University Clinic (Oncology/Haematology), Hamburg, , Germany

St. Marien Hospital, Klinik fur Hamatologie und Onkologie, Hamm, , Germany

Universitatsklinikum Heidelberg, Abt. Fur Haematologie und Onkologie, Heidelberg, , Germany

University of Essen Medical School, Dept. of Internal Medicine, Hufelandstr, , Germany

Johannes Gutenberg-Universitat Mainz, III. Med Klinik und Poliknik, Mainz, , Germany

Uniklinikum Muenster, Muenster, , Germany

Eberhard-Karls Universitat, Medizinische Klinik, Tubingen, , Germany

Belfast City Hospital, Belfast, , Ireland

RAMBAM Medical Center, Department of Hematology and Bone, Haifa, , Israel

Hadassah University Hospital, Jerusalem, , Israel

Dipartmento Clinico esperimentale Di Oncologia et Ematolgia, Bergamo, , Italy

Instituto di Ematologia e Oncologia Medica, Lorenzo e Ariosto Seragnoli, Bologna, , Italy

Dipartimento di Biotecnologie Cellulari ed Ematologia, Roma, , Italy

Azienda Ospedaliera, S. Giovanni Battista, Torino, , Italy

Dept. of Clinical Hematology, Academic Medical Center, Amsterdam, , Netherlands

Department of Hematology, Erasmus MC, 1a, Daniel Den Hoed, Rotterdam, , Netherlands

Dept. Hematology, University Medical Centre, Utrecht, , Netherlands

Hospital Clinico Universitario de Barcelona, Haematology Department, Barcelona, , Spain

University Hospital of Salamanca, Salamanca, , Spain

Department of Haematology, Huddinge University Hospital M54, Stockholm, , Sweden

Karolinska Hospital, Dept. of Hematology, Stockholm, , Sweden

Adult Leukaemia Unit, Christie Hospital, Withington, Manchester, United Kingdom

Department of Haematology, Queen Elizabeth Hospital, Birmingham, , United Kingdom

Leeds General Infirmary, Leeds, , United Kingdom

Department of Haematology, St. Bartholomew's Hospital, London, , United Kingdom

Department of Haematology, ICSM, Hammersmith Hospital, London, , United Kingdom

Royal Marsden Hospital, Leukaemia and Myeloma Units, Sutton, , United Kingdom

Contact Details

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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