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Brief Title: Phase 1b Study of Weekly Carfilzomib in Combination With Lenalidomide and Dexamethasone in Subjects With Multiple Myeloma
Official Title: Phase 1b Study of Carfilzomib Administered Once Weekly in Combination With Lenalidomide and Dexamethasone in Subjects With Multiple Myeloma
Study ID: NCT02335983
Brief Summary: The purpose of the study is to assess the safety, tolerability and activity of a once-weekly regimen of carfilzomib in combination with lenalidomide and dexamethasone for the treatment of multiple myeloma.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Research Site, Bakersfield, California, United States
CBCC Global Research, Inc. at Comprehensive Blood and Cancer Center, Bakersfield, California, United States
Research Site, Burbank, California, United States
Providence Saint Joseph Medical Center, Burbank, California, United States
Research Site, Fountain Valley, California, United States
Compassionate Care Research Group, Inc., Fountain Valley, California, United States
Research Site, Los Angeles, California, United States
Research Site, Los Angeles, California, United States
Los Angeles Hematology / Oncology Medical Group, Los Angeles, California, United States
Research Site, Whittier, California, United States
Research Site, Aurora, Colorado, United States
University of Colorado, Aurora, Colorado, United States
Research Site, Washington, District of Columbia, United States
Lombardi Cancer Center, Pediatric Hematology Oncology, Washington, District of Columbia, United States
Research Site, Fort Myers, Florida, United States
Florida Cancer Specialists, Fort Myers, Florida, United States
Research Site, Tampa, Florida, United States
H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, United States
Research Site, West Palm Beach, Florida, United States
Florida Cancer Specialists, West Palm Beach, Florida, United States
University of Chicago Medical Center, Chicago, Illinois, United States
Research Site, Boston, Massachusetts, United States
Dana Farber Partners Cancer Care, Boston, Massachusetts, United States
Research Site, Ann Arbor, Michigan, United States
Research Site, Hackensack, New Jersey, United States
John Theurer Cancer Center at Hackensack University Medical Center, Hackensack, New Jersey, United States
Research Site, New York, New York, United States
Research Site, New York, New York, United States
Clinical Research Alliance, New York, New York, United States
Memorial Sloan Kettering, New York, New York, United States
Morton Coleman, MD, New York, New York, United States
Weill Cornell Medical College, New York, New York, United States
Research Site, Stony Brook, New York, United States
Stony Brook University Medical Center, Stony Brook, New York, United States
Research Site, Durham, North Carolina, United States
Durham Veterans Affairs Medical Center, Durham, North Carolina, United States
Research Site, Cincinnati, Ohio, United States
Sarah Cannon Research Institute, Cincinnati, Ohio, United States
Research Site, Bend, Oregon, United States
Bend Memorial Clinic, Bend, Oregon, United States
Research Site, Charleston, South Carolina, United States
Medical University of South Carolina, Hollings Cancer Center, Charleston, South Carolina, United States
Research Site, Greenville, South Carolina, United States
Greenville Health System, Greenville, South Carolina, United States
Saint Francis Hospital Cancer Center, Greenville, South Carolina, United States
Research Site, Sioux Falls, South Dakota, United States
Avera Cancer Institute, Sioux Falls, South Dakota, United States
Research Site, Germantown, Tennessee, United States
The West Clinic, PC, Memphis, Tennessee, United States
Research Site, Nashville, Tennessee, United States
Research Site, Nashville, Tennessee, United States
Tennessee Oncology, PLLC / The Sarah Cannon Research lnstitute, Nashville, Tennessee, United States
Vanderbilt University Medical Center, Nashville, Tennessee, United States
Research Site, Salt Lake City, Utah, United States
Huntsman Cancer Institute, Salt Lake City, Utah, United States
Research Site, Seattle, Washington, United States
Swedish Cancer Institute, Seattle, Washington, United States
Aurora Health Care, Aurora Cancer Care, Milwaukee, Wisconsin, United States
Research Site, Wauwatosa, Wisconsin, United States
Name: Amy Kimball, MD
Affiliation: Amgen
Role: STUDY_DIRECTOR