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Brief Title: A Study to Determine the Efficacy, Safety and Pharmacokinetics of GMI-1271 as Adjunct to Standard of Care for the Treatment of Multiple Myeloma
Official Title: A Phase I Open-Label Dose Escalation Study to Determine the Efficacy, Safety and Pharmacokinetics of GMI-1271 as Adjunct to Standard of Care Chemotherapy for the Treatment of Multiple Myeloma
Study ID: NCT02811822
Brief Summary: This study will evaluate GMI-1271, a specific E-selectin antagonist, in multiple myeloma as adjunct to standard of care chemotherapy used to treat this disease.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Vejle Hospital, Vejle, , Denmark
Medizinische Klinik/Abt. Innere Medizin V, Heidelberg, , Germany
Cork University Hospital, Wilton, Cork, , Ireland
Beaumont Hospital, Dublin, , Ireland
National University Ireland - Galway, Galway, , Ireland
Sheffield Teaching Hospital, Sheffield, England, United Kingdom
Saint James's University Hospital Leeds, Leeds, , United Kingdom
University College London Hospitals, London, , United Kingdom
Name: Michael O'Dwyer, MD
Affiliation: National University Ireland - Galway
Role: PRINCIPAL_INVESTIGATOR