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Brief Title: A Study of Teclistamab With Other Anticancer Therapies in Participants With Multiple Myeloma
Official Title: A Multi-arm Phase 1b Study of Teclistamab With Other Anticancer Therapies in Participants With Multiple Myeloma
Study ID: NCT04722146
Brief Summary: The purpose of this study is to characterize the safety and tolerability of teclistamab when administered in different combination regimen and to identify the optimal dose(s) of teclistamab combination regimens.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
University of Alabama at Birmingham, Birmingham, Alabama, United States
University of California San Francisco, San Francisco, California, United States
Colorado Blood Cancer Institute, Denver, Colorado, United States
Emory University, Atlanta, Georgia, United States
Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, Indiana, United States
Washington University School of Medicine, Saint Louis, Missouri, United States
Hackensack University Medical Center, Hackensack, New Jersey, United States
Memorial Sloan-Kettering Cancer Center, New York, New York, United States
Weill Cornell Medical College, New York, New York, United States
Levine Cancer Institute, Charlotte, North Carolina, United States
University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States
Tennessee Oncology, Nashville, Tennessee, United States
Seattle Cancer Care Alliance, Seattle, Washington, United States
Medical College Of Wisconsin, Milwaukee, Wisconsin, United States
St. Vincent's Hospital Melbourne, Fitzroy, , Australia
Alfred Health, Melbourne, , Australia
Calvary Mater Newcastle Hospital, Waratah, , Australia
UZA, Edegem, , Belgium
UZ Gent, Gent, , Belgium
Centre Leon Berard, Lyon Cedex 8, , France
CHU Nantes, Nantes Cedex 1, , France
CHU de Bordeaux - Hospital Haut-Leveque, Pessac cedex, , France
Chu Rennes Hopital Pontchaillou, Rennes, , France
Institut Universitaire du cancer de Toulouse-Oncopole, TOULOUSE Cedex 9, , France
University College Hospital, London, , United Kingdom
The Christie Nhs Foundation Trust, Manchester, , United Kingdom
The Royal Marsden NHS Trust Sutton, Surrey, , United Kingdom
Name: Janssen Research and Development, LLC Clinical Trial
Affiliation: Janssen Research and Development LLC
Role: STUDY_DIRECTOR